Biomolecular Measurement Science

IBBR has a robust set of capabilities in biomolecular measurement sciences – know-how and equipment that enable IBBR researchers to push the frontiers of high-resolution structural biology in therapeutically relevant proteins and protein complexes (e.g. glycol- and transmembrane proteins). This includes the capability to determine high-resolution structures of proteins, nucleic acids and biomolecular complexes (protein-protein and protein-nucleic acid) using macromolecular crystallography and solution-state NMR.

IBBR has access to major infrastructure comprising one of the nation’s largest collections of high-resolution instrumentation for studying macromolecular structure and function, including:

  • Keck/NIST Laboratory for Structural Biology (Ultra high field NMR (900 MHz))
  • Center for Biomolecular Therapeutics Structural Biology (Ultra high field NMR (800, 950 MHz))
  • NIST Center for Neutron Research (Ultra high sensitivity scattering instruments for biological samples)
  • X-ray diffraction

Research Faculty