IBBR Publications

Li SShun, Ogbomo H, Mansour MK, Xiang RF, Szabo L, Munro F, Mukherjee P, Mariuzza RA, Amrein M, Vyas JM, et al. Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida. Nat Commun. 2018 ;9(1):751.

Kardava L, Sohn H, Youn C, Austin JW, Wang W, Buckner CM, J Justement S, Melson VA, Roth GE, Hand MA, et al. IgG3 regulates tissue-like memory B cells in HIV-infected individuals. Nat Immunol. 2018 ;19(9):1001-1012.

Guan Y, Tsao C-Y, Quan DN, Li Y, Mei L, Zhang J, Zhang B, Liu Y, Bentley WE, Payne GF, et al. An immune magnetic nano-assembly for specifically amplifying intercellular quorum sensing signals. Colloids Surf B Biointerfaces. 2018 ;172:197-206.

Lin F-Y, Mackerell AD. Improved Modeling of Halogenated Ligand-Protein Interactions using the Drude Polarizable and CHARMM Additive Empirical Force Fields. J Chem Inf Model. 2018 .

Mailly L, Wrensch F, Heydmann L, Fauvelle C, Brignon N, Zeisel MB, Pessaux P, Keck Z-Y, Schuster C, Fuerst TR, et al. In vivo combination of human anti-envelope glycoprotein E2 and -Claudin-1 monoclonal antibodies for prevention of hepatitis C virus infection. Antiviral Res. 2018 .

Mishra AK, Mariuzza RA. Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing. Front Immunol. 2018 ;9:117.

Dai H-Y, Ma Y, Da Z, Hou X-M. Knockdown of TRIM66 inhibits malignant behavior and epithelial-mesenchymal transition in non-small cell lung cancer. Pathol Res Pract. 2018 .

Chu S, Winkler TE, Brown ADegen, Culver JN, Ghodssi R. Localized 3-D Functionalization of Bionanoreceptors on High-Density Micropillar Arrays via Electrowetting. Langmuir. 2018 .

Le Keck M-, Wrensch F, Pierce BG, Baumert TF, Foung SKH. Mapping Determinants of Virus Neutralization and Viral Escape for Rational Design of a Hepatitis C Virus Vaccine. Front Immunol. 2018 ;9:1194.

Rhoads MK, Hauk P, Gupta V, Bookstaver ML, Stephens K, Payne GF, Bentley WE. Modification and Assembly of a Versatile Lactonase for Bacterial Quorum Quenching. Molecules. 2018 ;23(2).

Huang J, Lemkul JA, Eastman PK, Mackerell AD. Molecular dynamics simulations using the drude polarizable force field on GPUs with OpenMM: Implementation, validation, and benchmarks. J Comput Chem. 2018 .

Huang Y-Y, Zhang L-L, Ma X-F, Zhao Z-X, Zhao J-H, Zhao J-Q, Fan J, Li Y, He P, Xiao S, et al. Multiple intramolecular trafficking signals in RESISTANCE TO POWDERY MILDEW 8.2 are engaged in activation of cell death and defense. Plant J. 2018 .

Ashkar R, Bilheux HZ, Bordallo H, Briber R, Callaway DJE, Cheng X, Chu XQiang, Curtis JE, Dadmun M, Fenimore P, et al. Neutron scattering in the biological sciences: progress and prospects. Acta Crystallogr D Struct Biol. 2018 ;74(Pt 12):1129-1168.

Schiel JE, Turner A. The NISTmAb Reference Material 8671 lifecycle management and quality plan. Anal Bioanal Chem. 2018 ;410(8):2067-2078.

Schiel JE, Turner A, Mouchahoir T, Yandrofski K, Telikepalli S, King J, DeRose P, Ripple D, Phinney K. The NISTmAb Reference Material 8671 value assignment, homogeneity, and stability. Anal Bioanal Chem. 2018 ;410(8):2127-2139.

Zambrello MA, Schuyler AD, Maciejewski MW, Delaglio F, Bezsonova I, Hoch JC. Nonuniform Sampling in Multidimensional NMR for Improving Spectral Sensitivity. Methods. 2018 .

Boulanger E, Huang L, Rupakheti C, Mackerell AD, Roux B. Optimized Lennard-Jones Parameters for Druglike Small Molecules. J Chem Theory Comput. 2018 .

Lin X, Roy S, Jolly MKumar, Bocci F, Schafer NP, Tsai M-Y, Chen Y, He Y, Grishaev A, Weninger K, et al. PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer. J Mol Biol. 2018 .

Rangarajan S, He Y, Chen Y, Kerzic MC, Ma B, Gowthaman R, Pierce BG, Nussinov R, Mariuzza RA, Orban J. Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites. J Biol Chem. 2018 .

Jolly MKumar, Kulkarni P, Weninger K, Orban J, Levine H. Phenotypic Plasticity, Bet-Hedging, and Androgen Independence in Prostate Cancer: Role of Non-Genetic Heterogeneity. Front Oncol. 2018 ;8:50.

Reddy PT, Brinson RG, J Hoopes T, McClung C, Ke N, Kashi L, Berkmen M, Kelman Z. Platform development for expression and purification of stable isotope labeled monoclonal antibodies in Escherichia coli. MAbs. 2018 :1-11.

Mckay R, Ghodasra M, Schardt J, Quan D, Pottash AEli, Shang W, Jay SM, Payne GF, Chang MWook, March JC, et al. A platform of genetically engineered bacteria as vehicles for localized delivery of therapeutics: Toward applications for Crohn's disease. Bioeng Transl Med. 2018 ;3(3):209-221.

Lemkul JA, Mackerell AD. Polarizable force field for RNA based on the classical drude oscillator. J Comput Chem. 2018 ;39(32):2624-2646.

Brocke S, Degen A, Mackerell AD, Dutagaci B, Feig M. Prediction of Membrane Permeation of Drug Molecules by Combining an Implicit Membrane Model with Machine Learning. J Chem Inf Model. 2018 .

Reid W, Pilitt K, Alford R, Cervantes-Medina A, Yu H, Aluvihare C, Harrell R, O'Brochta DA. An Promoter-Trap: Augmenting Genome Annotation and Functional Genomics. G3 (Bethesda). 2018 .