IBBR Publications

Found 620 results
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2008
Muro S, Garnacho C, Champion JA, Leferovich J, Gajewski C, Schuchman EH, Mitragotri S, Muzykantov VR. Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers. Mol Ther. 2008 ;16(8):1450-8.
Garnacho C, Dhami R, Simone E, Dziubla T, Leferovich J, Schuchman EH, Muzykantov V, Muro S. Delivery of acid sphingomyelinase in normal and niemann-pick disease mice using intercellular adhesion molecule-1-targeted polymer nanocarriers. J Pharmacol Exp Ther. 2008 ;325(2):400-8.
Gediya LK, Khandelwal A, Patel J, Belosay A, Sabnis G, Mehta J, Purushottamachar P, Njar VCO. Design, synthesis, and evaluation of novel mutual prodrugs (hybrid drugs) of all-trans-retinoic acid and histone deacetylase inhibitors with enhanced anticancer activities in breast and prostate cancer cells in vitro. J Med Chem. 2008 ;51(13):3895-904.
Charpentier TH, Wilder PT, Liriano MA, Varney KM, Pozharski E, Mackerell AD, Coop A, Toth EA, Weber DJ. Divalent metal ion complexes of S100B in the absence and presence of pentamidine. J Mol Biol. 2008 ;382(1):56-73.
Stoltzfus A. Evidence for a predominant role of oxidative damage in germline mutation in mammals. Mutat Res. 2008 ;644(1-2):71-3.
Xu Y, Colletier J-P, Weik M, Jiang H, Moult J, Silman I, Sussman JL. Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics. Biophys J. 2008 ;95(5):2500-11.
Selvarajah S, Puffer BA, Lee F-H, Zhu P, Li Y, Wyatt R, Roux KH, Doms RW, Burton DR. Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140. AIDS Res Hum Retroviruses. 2008 ;24(2):301-14.
Yu W-M, Guvench O, Mackerell AD, Qu C-K. Identification of small molecular weight inhibitors of Src homology 2 domain-containing tyrosine phosphatase 2 (SHP-2) via in silico database screening combined with experimental assay. J Med Chem. 2008 ;51(23):7396-404.
Gediya LK, Belosay A, Khandelwal A, Purushottamachar P, Njar VCO. Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts. Bioorg Med Chem. 2008 ;16(6):3352-60.
Rossin R, Muro S, Welch MJ, Muzykantov VR, Schuster DP. In vivo imaging of 64Cu-labeled polymer nanoparticles targeted to the lung endothelium. J Nucl Med. 2008 ;49(1):103-11.
Gawrisch K, Soubias O, Mihailescu M. Insights from biophysical studies on the role of polyunsaturated fatty acids for function of G-protein coupled membrane receptors. Prostaglandins Leukot Essent Fatty Acids. 2008 ;79(3-5):131-4.
Pal S, Wu J, Wu LP. Microarray analyses reveal distinct roles for Rel proteins in the Drosophila immune response. Dev Comp Immunol. 2008 ;32(1):50-60.
Chlewicki LK, Velikovsky CA, Balakrishnan V, Mariuzza RA, Kumar V. Molecular basis of the dual functions of 2B4 (CD244). J Immunol. 2008 ;180(12):8159-67.
Ozhogina OA, Grishaev A, Bominaar EL, Patthy L, Trexler M, Llinás M. NMR solution structure of the neurotrypsin Kringle domain. Biochemistry. 2008 ;47(47):12290-8.
Pancer Z, Mariuzza RA. The oldest antibodies newly discovered. Nat Biotechnol. 2008 ;26(4):402-3.
O'Brochta DA, Handler AM. Perspectives on the state of insect transgenics. Adv Exp Med Biol. 2008 ;627:1-18.
Hwang H, Pierce BG, Mintseris J, Janin J, Weng Z. Protein-protein docking benchmark version 3.0. Proteins. 2008 ;73(3):705-9.
Wiehe K, Peterson MW, Pierce BG, Mintseris J, Weng Z. Protein-protein docking: overview and performance analysis. Methods Mol Biol. 2008 ;413:283-314.
Wright NT, Inman KG, Levine JA, Cannon BR, Varney KM, Weber DJ. Refinement of the solution structure and dynamic properties of Ca(2+)-bound rat S100B. J Biomol NMR. 2008 ;42(4):279-86.
Regier JC, Shultz JW, Ganley ARD, Hussey A, Shi D, Ball B, Zwick A, Stajich JE, Cummings MP, Martin JW, et al. Resolving arthropod phylogeny: exploring phylogenetic signal within 41 kb of protein-coding nuclear gene sequence. Syst Biol. 2008 ;57(6):920-38.
Garnacho C, Shuvaev V, Thomas A, McKenna L, Sun J, Koval M, Albelda S, Muzykantov V, Muro S. RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1. Blood. 2008 ;111(6):3024-33.
Wright NT, Prosser BL, Varney KM, Zimmer DB, Schneider MF, Weber DJ. S100A1 and calmodulin compete for the same binding site on ryanodine receptor. J Biol Chem. 2008 ;283(39):26676-83.
Prosser BL, Wright NT, Hernández-Ochoa EO, Varney KM, Liu Y, Olojo RO, Zimmer DB, Weber DJ, Schneider MF. S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling. J Biol Chem. 2008 ;283(8):5046-57.
Vanderah DJ, Walker ML, Rocco MA, Rubinson KA. Self-assembled monolayers of an oligo(ethylene oxide) disulfide and its corresponding thiol assembled from water: characterization and protein resistance. Langmuir. 2008 ;24(3):826-9.
Baniulis D, Yamashita E, Zhang H, S Hasan S, Cramer WA. Structure-function of the cytochrome b6f complex. Photochem Photobiol. 2008 ;84(6):1349-58.