IBBR Publications

Found 524 results
Filters: Keyword is Humans  [Clear All Filters]
Ballin JD, Prevas JP, Ross CR, Toth EA, Wilson GM, M Record T. Contributions of the histidine side chain and the N-terminal alpha-amino group to the binding thermodynamics of oligopeptides to nucleic acids as a function of pH. Biochemistry. 2010 ;49(9):2018-30.
Shen Y, Bryan PN, He Y, Orban J, Baker D, Bax A. De novo structure generation using chemical shifts for proteins with high-sequence identity but different folds. Protein Sci. 2010 ;19(2):349-56.
Yung CWing, Bentley WE, Barbari TA. Diffusion of interleukin-2 from cells overlaid with cytocompatible enzyme-crosslinked gelatin hydrogels. J Biomed Mater Res A. 2010 ;95(1):25-32.
Charpentier TH, Thompson LE, Liriano MA, Varney KM, Wilder PT, Pozharski E, Toth EA, Weber DJ. The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography. J Mol Biol. 2010 ;396(5):1227-43.
Yoo MJ, Schiel JE, Hage DS. Evaluation of affinity microcolumns containing human serum albumin for rapid analysis of drug-protein binding. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 ;878(20):1707-13.
Stains CI, Furman JL, Porter JR, Rajagopal S, Li Y, Wyatt RT, Ghosh I. A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly. ACS Chem Biol. 2010 ;5(10):943-52.
Carmel R, Bellevue R, Kelman Z. Low cobalamin levels associated with sickle cell disease: Contrasting origins and clinical meanings in two instructive patients. Am J Hematol. 2010 ;85(6):436-9.
Rais R, Acharya C, Tririya G, Mackerell AD, Polli JE. Molecular switch controlling the binding of anionic bile acid conjugates to human apical sodium-dependent bile acid transporter. J Med Chem. 2010 ;53(12):4749-60.
Muro S. New biotechnological and nanomedicine strategies for treatment of lysosomal storage disorders. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 ;2(2):189-204.
Vasaitis TS, Njar VCO. Novel, potent anti-androgens of therapeutic potential: recent advances and promising developments. Future Med Chem. 2010 ;2(4):667-80.
Malashkevich VN, Dulyaninova NG, Ramagopal UA, Liriano MA, Varney KM, Knight D, Brenowitz M, Weber DJ, Almo SC, Bresnick AR. Phenothiazines inhibit S100A4 function by inducing protein oligomerization. Proc Natl Acad Sci U S A. 2010 ;107(19):8605-10.
Bryan PN, Orban J. Proteins that switch folds. Curr Opin Struct Biol. 2010 ;20(4):482-8.
Roltsch E, Holcomb L, Young KA, Marks A, Zimmer DB. PSAPP mice exhibit regionally selective reductions in gliosis and plaque deposition in response to S100B ablation. J Neuroinflammation. 2010 ;7:78.
Wu X, Yang Z-Y, Li Y, Hogerkorp C-M, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science. 2010 ;329(5993):856-61.
Ofek GA, McKee K, Yang Y, Yang Z-Y, Skinner J, F Guenaga J, Wyatt R, Zwick MB, Nabel GJ, Mascola JR, et al. Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region. J Virol. 2010 ;84(6):2955-62.
Cerchietti LC, Ghetu AF, Zhu X, Da Silva GF, Zhong S, Matthews M, Bunting KL, Polo JM, Farès C, Arrowsmith CH, et al. A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo. Cancer Cell. 2010 ;17(4):400-11.
Lim K, Pullalarevu S, Surabian KTalin, Howard A, Suzuki T, Moult J, Herzberg O. Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member. Biochemistry. 2010 ;49(9):2031-41.
Li Y, Depontieu FR, Sidney J, Salay TM, Engelhard VH, Hunt DF, Sette A, Topalian SL, Mariuzza RA. Structural basis for the presentation of tumor-associated MHC class II-restricted phosphopeptides to CD4+ T cells. J Mol Biol. 2010 ;399(4):596-603.
Rais R, Acharya C, Mackerell AD, Polli JE. Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates. Mol Pharm. 2010 ;7(6):2240-54.
Luncsford PJ, Chang D-Y, Shi G, Bernstein J, Madabushi A, Patterson DN, Lu A-L, Toth EA. A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. J Mol Biol. 2010 ;403(3):351-70.
Swanson HI, Njar VCO, Yu Z, Castro DJ, Gonzalez FJ, Williams DE, Huang Y, Kong A-NT, Doloff JC, Ma J, et al. Targeting drug-metabolizing enzymes for effective chemoprevention and chemotherapy. Drug Metab Dispos. 2010 ;38(4):539-44.
Semenyuk A, Darian E, Liu J, Majumdar A, Cuenoud B, Miller PS, Mackerell AD, Seidman MM. Targeting of an interrupted polypurine:polypyrimidine sequence in mammalian cells by a triplex-forming oligonucleotide containing a novel base analogue. Biochemistry. 2010 ;49(36):7867-78.