IBBR Publications

Found 524 results
Filters: Keyword is Humans  [Clear All Filters]
2013
Hong X, Ma MZ, Gildersleeve JC, Chowdhury S, Barchi JJ, Mariuzza RA, Murphy MB, Mao L, Pancer Z. Sugar-binding proteins from fish: selection of high affinity "lambodies" that recognize biomedically relevant glycans. ACS Chem Biol. 2013 ;8(1):152-60.
Healy JR, Bezawada P, Shim J, Jones JW, Kane MA, Mackerell AD, Coop A, Matsumoto RR. Synthesis, modeling, and pharmacological evaluation of UMB 425, a mixed μ agonist/δ antagonist opioid analgesic with reduced tolerance liabilities. ACS Chem Neurosci. 2013 ;4(9):1256-66.
Purushottamachar P, Godbole AM, Gediya LK, Martin MS, Vasaitis TS, Kwegyir-Afful AK, Ramalingam S, Ates-Alagoz Z, Njar VCO. Systematic structure modifications of multitarget prostate cancer drug candidate galeterone to produce novel androgen receptor down-regulating agents as an approach to treatment of advanced prostate cancer. J Med Chem. 2013 ;56(12):4880-98.
Yu B, Liu W, Yu W-M, Loh ML, Alter S, Guvench O, Mackerell AD, Da Tang L-, Qu C-K. Targeting protein tyrosine phosphatase SHP2 for the treatment of PTPN11-associated malignancies. Mol Cancer Ther. 2013 ;12(9):1738-48.
Sabit H, Mallajosyula SS, Mackerell AD, Swaan PW. Transmembrane domain II of the human bile acid transporter SLC10A2 coordinates sodium translocation. J Biol Chem. 2013 ;288(45):32394-404.
Varney KM, Bonvin AMJJ, Pazgier M, Malin J, Yu W, Ateh E, Oashi T, Lu W, Huang J, de Buin MDiepeveen-, et al. Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid II. PLoS Pathog. 2013 ;9(11):e1003732.
Erzurumlu Y, Kose FAydin, Gozen O, Gozuacik D, Toth EA, Ballar P. A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization. Int J Biochem Cell Biol. 2013 ;45(4):773-82.
2012
Wang M, Chen J, Turko IV. 15N-labeled full-length apolipoprotein E4 as an internal standard for mass spectrometry quantification of apolipoprotein E isoforms. Anal Chem. 2012 ;84(19):8340-4.
Han J, Zern BJ, Shuvaev VV, Davies PF, Muro S, Muzykantov V. Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1. ACS Nano. 2012 ;6(10):8824-36.
Godbole AM, Purushottamachar P, Martin MS, Daskalakis C, Njar VCO. Autophagy inhibition synergistically enhances anticancer efficacy of RAMBA, VN/12-1 in SKBR-3 cells, and tumor xenografts. Mol Cancer Ther. 2012 ;11(4):898-908.
Zhang F, Liang X, Pu D, George KI, Holland PJ, Walsh STR, Linhardt RJ. Biophysical characterization of glycosaminoglycan-IL-7 interactions using SPR. Biochimie. 2012 ;94(1):242-9.
Huang J, Ofek GA, Laub L, Louder MK, Doria-Rose NA, Longo NS, Imamichi H, Bailer RT, Chakrabarti B, Sharma SK, et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature. 2012 ;491(7424):406-12.
Muro S. Challenges in design and characterization of ligand-targeted drug delivery systems. J Control Release. 2012 ;164(2):125-37.
Yin Y, Wang XXiang, Mariuzza RA. Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proc Natl Acad Sci U S A. 2012 ;109(14):5405-10.
Manvilla BA, Maiti A, Begley MC, Toth EA, Drohat AC. Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA. J Mol Biol. 2012 ;420(3):164-75.
Chao KL, Tsai I-W, Chen C, Herzberg O. Crystal structure of the Sema-PSI extracellular domain of human RON receptor tyrosine kinase. PLoS One. 2012 ;7(7):e41912.
Hawse WF, Champion MM, Joyce MV, Hellman LM, Hossain M, Ryan V, Pierce BG, Weng Z, Baker BM. Cutting edge: Evidence for a dynamically driven T cell signaling mechanism. J Immunol. 2012 ;188(12):5819-23.
Suhasini AN, Sommers JA, Yu S, Wu Y, Xu T, Kelman Z, Kaplan DL, Brosh RM. DNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion. J Biol Chem. 2012 ;287(23):19188-98.
Bhowmick T, Berk E, Cui X, Muzykantov VR, Muro S. Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1. J Control Release. 2012 ;157(3):485-92.
Hsu J, Northrup L, Bhowmick T, Muro S. Enhanced delivery of α-glucosidase for Pompe disease by ICAM-1-targeted nanocarriers: comparative performance of a strategy for three distinct lysosomal storage disorders. Nanomedicine. 2012 ;8(5):731-9.
Chu SW, Noyes MB, Christensen RG, Pierce BG, Zhu LJ, Weng Z, Stormo GD, Wolfe SA. Exploring the DNA-recognition potential of homeodomains. Genome Res. 2012 ;22(10):1889-98.
Kilpatrick EL, Liao W-L, Camara JE, Turko IV, Bunk DM. Expression and characterization of 15N-labeled human C-reactive protein in Escherichia coli and Pichia pastoris for use in isotope-dilution mass spectrometry. Protein Expr Purif. 2012 ;85(1):94-9.
Heo G-Y, Liao W-L, Turko IV, Pikuleva IA. Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1. Arch Biochem Biophys. 2012 ;518(2):119-26.
Garnacho C, Serrano D, Muro S. A fibrinogen-derived peptide provides intercellular adhesion molecule-1-specific targeting and intraendothelial transport of polymer nanocarriers in human cell cultures and mice. J Pharmacol Exp Ther. 2012 ;340(3):638-47.
Purushottamachar P, Patel JB, Gediya LK, Clement OO, Njar VCO. First chemical feature-based pharmacophore modeling of potent retinoidal retinoic acid metabolism blocking agents (RAMBAs): identification of novel RAMBA scaffolds. Eur J Med Chem. 2012 ;47(1):412-23.