IBBR Publications

Altieri AS, Ladner JE, Li Z, Robinson H, Sallman ZF, Marino JP, Kelman Z. A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res. 2016 ;44(13):6232-41.

Ladner JE, Atanasova V, Dolezelova Z, Parsons JF. Structure and activity of PA5508, a hexameric glutamine synthetase homologue. Biochemistry. 2012 ;51(51):10121-3.

Bera AK, Atanasova V, Dhanda A, Ladner JE, Parsons JF. Structure of aminodeoxychorismate synthase from Stenotrophomonas maltophilia. Biochemistry. 2012 ;51(51):10208-17.

Ladner JE, Pan M, Hurwitz J, Kelman Z. Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc Natl Acad Sci U S A. 2011 ;108(7):2711-6.

Stourman NV, Branch MC, Schaab MR, Harp JM, Ladner JE, Armstrong RN. Structure and function of YghU, a nu-class glutathione transferase related to YfcG from Escherichia coli. Biochemistry. 2011 ;50(7):1274-81.

Wadington MC, Ladner JE, Stourman NV, Harp JM, Armstrong RN. Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase. Biochemistry. 2009 ;48(28):6559-61.

Kim S-K, Reddy SK, Nelson BC, Robinson H, Reddy PT, Ladner JE. A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H(37)R(v) and the secreted chorismate mutase (y2828) from Yersinia pestis. FEBS J. 2008 ;275(19):4824-35.

Greenhagen BT, Shi K, Robinson H, Gamage S, Bera AK, Ladner JE, Parsons JF. Crystal structure of the pyocyanin biosynthetic protein PhzS. Biochemistry. 2008 ;47(19):5281-9.

Parsons JF, Shi KM, Ladner JE. Structure of isochorismate synthase in complex with magnesium. Acta Crystallogr D Biol Crystallogr. 2008 ;64(Pt 5):607-10.

Thompson LC, Ladner JE, Codreanu SG, Harp J, Gilliland GL, Armstrong RN. 2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomonas putida. Biochemistry. 2007 ;46(23):6710-22.

Parsons JF, Greenhagen BT, Shi K, Calabrese K, Robinson H, Ladner JE. Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. Biochemistry. 2007 ;46(7):1821-8.

Kim S-K, Reddy SK, Nelson BC, Vasquez GB, Davis A, Howard AJ, Patterson S, Gilliland GL, Ladner JE, Reddy PT. Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids. J Bacteriol. 2006 ;188(24):8638-48.

Parsons JF, Shi K, Calabrese K, Ladner JE. Crystallization and X-ray diffraction analysis of salicylate synthase, a chorismate-utilizing enyme involved in siderophore biosynthesis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 ;62(Pt 3):271-4.

Ladner JE, Parsons JF, Rife CL, Gilliland GL, Armstrong RN. Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochondrial class kappa enzyme rGSTK1-1. Biochemistry. 2004 ;43(2):352-61.

Parsons JF, Song F, Parsons L, Calabrese K, Eisenstein E, Ladner JE. Structure and function of the phenazine biosynthesis protein PhzF from Pseudomonas fluorescens 2-79. Biochemistry. 2004 ;43(39):12427-35.

Parsons JF, Calabrese K, Eisenstein E, Ladner JE. Structure of the phenazine biosynthesis enzyme PhzG. Acta Crystallogr D Biol Crystallogr. 2004 ;60(Pt 11):2110-3.

Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, R Camerini-Otero D, Gilliland GL. Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site. BMC Struct Biol. 2003 ;3:7.

Parsons JF, Calabrese K, Eisenstein E, Ladner JE. Structure and mechanism of Pseudomonas aeruginosa PhzD, an isochorismatase from the phenazine biosynthetic pathway. Biochemistry. 2003 ;42(19):5684-93.

Gilliland GL, Tung M, Ladner JE. The Biological Macromolecule Crystallization Database: crystallization procedures and strategies. Acta Crystallogr D Biol Crystallogr. 2002 ;58(Pt 6 No 1):916-20.

Codreanu SG, Ladner JE, Xiao G, Stourman NV, Hachey DL, Gilliland GL, Armstrong RN. Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase. Biochemistry. 2002 ;41(51):15161-72.

Almog O, D Gallagher T, Ladner JE, Strausberg S, Alexander P, Bryan PN, Gilliland GL. Structural basis of thermostability. Analysis of stabilizing mutations in subtilisin BPN'. J Biol Chem. 2002 ;277(30):27553-8.

Parsons JF, Jensen PY, Pachikara AS, Howard AJ, Eisenstein E, Ladner JE. Structure of Escherichia coli aminodeoxychorismate synthase: architectural conservation and diversity in chorismate-utilizing enzymes. Biochemistry. 2002 ;41(7):2198-208.