IBBR Publications

Found 12 results
Filters: Author is Sintim, Herman O  [Clear All Filters]
2020
Hauk P, Stephens K, Virgile C, VanArsdale E, Pottash AEli, Schardt JS, Jay SM, Sintim HO, Bentley WE. Homologous Quorum Sensing Regulatory Circuit: A Dual-Input Genetic Controller for Modulating Quorum Sensing-Mediated Protein Expression in . ACS Synth Biol. 2020 ;9(10):2692-2702.
2018
Ha J-H, Hauk P, Cho K, Eo Y, Ma X, Stephens K, Cha S, Jeong M, Suh J-Y, Sintim HO, et al. Evidence of link between quorum sensing and sugar metabolism in revealed via cocrystal structures of LsrK and HPr. Sci Adv. 2018 ;4(6):eaar7063.
2016
Subramanian S, Gerasopoulos K, Guo M, Sintim HO, Bentley WE, Ghodssi R. Autoinducer-2 analogs and electric fields - an antibiotic-free bacterial biofilm combination treatment. Biomed Microdevices. 2016 ;18(5):95.
Hauk P, Stephens K, Mckay R, Virgile CRyan, Ueda H, Ostermeier M, Ryu K-S, Sintim HO, Bentley WE. Insightful directed evolution of Escherichia coli quorum sensing promoter region of the lsrACDBFG operon: a tool for synthetic biology systems and protein expression. Nucleic Acids Res. 2016 ;44(21):10515-10525.
2015
Zargar A, Quan DN, Carter KK, Guo M, Sintim HO, Payne GF, Bentley WE. Bacterial secretions of nonpathogenic Escherichia coli elicit inflammatory pathways: a closer investigation of interkingdom signaling. MBio. 2015 ;6(2):e00025.
Guo M, Zheng Y, Terell JL, Ad M, Opoku-Temeng C, Bentley WE, Sintim HO. Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators. Chem Commun (Camb). 2015 ;51(13):2617-20.
2013
Roy V, Meyer MT, Smith JAI, Gamby S, Sintim HO, Ghodssi R, Bentley WE. AI-2 analogs and antibiotics: a synergistic approach to reduce bacterial biofilms. Appl Microbiol Biotechnol. 2013 ;97(6):2627-38.
Ha J-H, Eo Y, Grishaev A, Guo M, Smith JAI, Sintim HO, Kim E-H, Cheong H-K, Bentley WE, Ryu K-S. Crystal structures of the LsrR proteins complexed with phospho-AI-2 and two signal-interrupting analogues reveal distinct mechanisms for ligand recognition. J Am Chem Soc. 2013 ;135(41):15526-35.
Adams BL, Carter KK, Guo M, Wu H-C, Tsao C-Y, Sintim HO, Valdes JJ, Bentley WE. Evolved Quorum Sensing Regulator, LsrR, for Altered Switching Functions. ACS Synth Biol. 2013 .
2012
Gamby S, Roy V, Guo M, Smith JAI, Wang J, Stewart JE, Wang X, Bentley WE, Sintim HO. Altering the communication networks of multispecies microbial systems using a diverse toolbox of AI-2 analogues. ACS Chem Biol. 2012 ;7(6):1023-30.
2011
Kamaraju K, Smith J, Wang J, Roy V, Sintim HO, Bentley WE, Sukharev S. Effects on membrane lateral pressure suggest permeation mechanisms for bacterial quorum signaling molecules. Biochemistry. 2011 ;50(32):6983-93.
2010
Roy V, Smith JAI, Wang J, Stewart JE, Bentley WE, Sintim HO. Synthetic analogs tailor native AI-2 signaling across bacterial species. J Am Chem Soc. 2010 ;132(32):11141-50.