IBBR Publications
Found 12 results
Filters: Author is Sintim, Herman O [Clear All Filters]
Homologous Quorum Sensing Regulatory Circuit: A Dual-Input Genetic Controller for Modulating Quorum Sensing-Mediated Protein Expression in . ACS Synth Biol. 2020 ;9(10):2692-2702.
. Evidence of link between quorum sensing and sugar metabolism in revealed via cocrystal structures of LsrK and HPr. Sci Adv. 2018 ;4(6):eaar7063.
Autoinducer-2 analogs and electric fields - an antibiotic-free bacterial biofilm combination treatment. Biomed Microdevices. 2016 ;18(5):95.
. Insightful directed evolution of Escherichia coli quorum sensing promoter region of the lsrACDBFG operon: a tool for synthetic biology systems and protein expression. Nucleic Acids Res. 2016 ;44(21):10515-10525.
. Bacterial secretions of nonpathogenic Escherichia coli elicit inflammatory pathways: a closer investigation of interkingdom signaling. MBio. 2015 ;6(2):e00025.
. Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators. Chem Commun (Camb). 2015 ;51(13):2617-20.
. AI-2 analogs and antibiotics: a synergistic approach to reduce bacterial biofilms. Appl Microbiol Biotechnol. 2013 ;97(6):2627-38.
. Crystal structures of the LsrR proteins complexed with phospho-AI-2 and two signal-interrupting analogues reveal distinct mechanisms for ligand recognition. J Am Chem Soc. 2013 ;135(41):15526-35.
. Evolved Quorum Sensing Regulator, LsrR, for Altered Switching Functions. ACS Synth Biol. 2013 .
. Altering the communication networks of multispecies microbial systems using a diverse toolbox of AI-2 analogues. ACS Chem Biol. 2012 ;7(6):1023-30.
. Effects on membrane lateral pressure suggest permeation mechanisms for bacterial quorum signaling molecules. Biochemistry. 2011 ;50(32):6983-93.
. Synthetic analogs tailor native AI-2 signaling across bacterial species. J Am Chem Soc. 2010 ;132(32):11141-50.
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