IBBR Publications
Found 22 results
Filters: Author is He, Yanan [Clear All Filters]
Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol. 2021 ;4(1):299.
Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs). J Mol Biol. 2020 ;432(24):166697.
. PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer. J Mol Biol. 2018 .
. . Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR. J Biol Chem. 2015 .
Phosphorylation-Induced Conformational Ensemble Switching in an Intrinsically Disordered Cancer/Testis Antigen. J Biol Chem. 2015 .
. Subdomain Interactions Foster the Design of Two Protein Pairs with ∼80% Sequence Identity but Different Folds. Biophys J. 2015 ;108(1):154-62.
. Mutational tipping points for switching protein folds and functions. Structure. 2012 ;20(2):283-91.
. Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum. Proteins. 2012 ;80(12):2810-7.
. The cancer/testis antigen prostate-associated gene 4 (PAGE4) is a highly intrinsically disordered protein. J Biol Chem. 2011 ;286(16):13985-94.
. De novo structure generation using chemical shifts for proteins with high-sequence identity but different folds. Protein Sci. 2010 ;19(2):349-56.
. A minimal sequence code for switching protein structure and function. Proc Natl Acad Sci U S A. 2009 ;106(50):21149-54.
. NMR structures of two designed proteins with high sequence identity but different fold and function. Proc Natl Acad Sci U S A. 2008 ;105(38):14412-7.
. An artificially evolved albumin binding module facilitates chemical shift epitope mapping of GA domain interactions with phylogenetically diverse albumins. Protein Sci. 2007 ;16(7):1490-4.
. The design and characterization of two proteins with 88% sequence identity but different structure and function. Proc Natl Acad Sci U S A. 2007 ;104(29):11963-8.
. Solution structure of HI1506, a novel two-domain protein from Haemophilus influenzae. Protein Sci. 2007 ;16(5):977-82.
. Structure, dynamics, and stability variation in bacterial albumin binding modules: implications for species specificity. Biochemistry. 2006 ;45(33):10102-9.
. Using offset recombinant polymerase chain reaction to identify functional determinants in a common family of bacterial albumin binding domains. Biochemistry. 2006 ;45(10):3263-71.
. Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds. Biochemistry. 2005 ;44(43):14055-61.
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