Publications

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Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition.
Maiti A, Morgan MT, Pozharski E, Drohat AC. 2008. Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition. Proceedings of the National Academy of Sciences of the United States of America 105(26): 8890-5. DOI: 10.1073/pnas.0711061105
Synthesis of novel C17 steroidal carbamates. Studies on CYP17 action, androgen receptor binding and function, and prostate cancer cell growth.
Moreira VM, Vasaitis TS, Guo Z, Njar VC, Salvador JA. 2008. Synthesis of novel C17 steroidal carbamates. Studies on CYP17 action, androgen receptor binding and function, and prostate cancer cell growth. Steroids 73(12): 1217-27. DOI: 10.1016/j.steroids.2008.05.010
Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
Witt AC, Lakshminarasimhan M, Remington BC, Hasim S, Pozharski E, Wilson MA. 2008. Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry 47(28): 7430-40. DOI: 10.1021/bi800282d
Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers.
Muro S, Garnacho C, Champion JA, Leferovich J, Gajewski C, Schuchman EH, Mitragotri S, Muzykantov VR. 2008. Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers. Molecular therapy : the journal of the American Society of Gene Therapy 16(8): 1450-8. DOI: 10.1038/mt.2008.127
Characterization of the solution structure of a neuroligin/beta-neurexin complex.
Comoletti D, Grishaev A, Whitten AE, Taylor P, Trewhella J. 2008. Characterization of the solution structure of a neuroligin/beta-neurexin complex. Chemico-biological interactions 175(1-3): 150-5. DOI: 10.1016/j.cbi.2008.04.040
Chitosan-coated electrodes for bimodal sensing: selective post-electrode film reaction for spectroelectrochemical analysis.
Liu Y, Gaskell KJ, Cheng Z, Yu LL, Payne GF. 2008. Chitosan-coated electrodes for bimodal sensing: selective post-electrode film reaction for spectroelectrochemical analysis. Langmuir : the ACS journal of surfaces and colloids 24(14): 7223-31. DOI: 10.1021/la800180y
Design, synthesis, and evaluation of novel mutual prodrugs (hybrid drugs) of all-trans-retinoic acid and histone deacetylase inhibitors with enhanced anticancer activities in breast and prostate cancer cells in vitro.
Gediya LK, Khandelwal A, Patel J, Belosay A, Sabnis G, Mehta J, Purushottamachar P, Njar VC. 2008. Design, synthesis, and evaluation of novel mutual prodrugs (hybrid drugs) of all-trans-retinoic acid and histone deacetylase inhibitors with enhanced anticancer activities in breast and prostate cancer cells in vitro. Journal of medicinal chemistry 51(13): 3895-904. DOI: 10.1021/jm8001839
Delivery systems for the targeted radiotherapy of cancer. Preface.
Sofou S, Yu YB. 2008. Delivery systems for the targeted radiotherapy of cancer. Preface. Advanced drug delivery reviews 60(12): 1317-8. DOI: 10.1016/j.addr.2008.04.004
Indole cell signaling occurs primarily at low temperatures in Escherichia coli.
Lee J, Zhang XS, Hegde M, Bentley WE, Jayaraman A, Wood TK. 2008. Indole cell signaling occurs primarily at low temperatures in Escherichia coli. The ISME journal 2(10): 1007-23. DOI: 10.1038/ismej.2008.54
Molecular basis of the dual functions of 2B4 (CD244).
Chlewicki LK, Velikovsky CA, Balakrishnan V, Mariuzza RA, Kumar V. 2008. Molecular basis of the dual functions of 2B4 (CD244). Journal of immunology (Baltimore, Md. : 1950) 180(12): 8159-67.
Soluble amyloid beta-oligomers affect dielectric membrane properties by bilayer insertion and domain formation: implications for cell toxicity.
Valincius G, Heinrich F, Budvytyte R, Vanderah DJ, McGillivray DJ, Sokolov Y, Hall JE, Lösche M. 2008. Soluble amyloid beta-oligomers affect dielectric membrane properties by bilayer insertion and domain formation: implications for cell toxicity. Biophysical journal 95(10): 4845-61. DOI: 10.1529/biophysj.108.130997
Engineering substrate preference in subtilisin: structural and kinetic analysis of a specificity mutant.
Ruan B, London V, Fisher KE, Gallagher DT, Bryan PN. 2008. Engineering substrate preference in subtilisin: structural and kinetic analysis of a specificity mutant. Biochemistry 47(25): 6628-36. DOI: 10.1021/bi800089f
Coagulation of tobacco mosaic virus in alcohol-water-LiCl solutions.
Lee SY, Lim JS, Culver JN, Harris MT. 2008. Coagulation of tobacco mosaic virus in alcohol-water-LiCl solutions. Journal of colloid and interface science 324(1-2): 92-8. DOI: 10.1016/j.jcis.2008.04.074
Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics.
Xu Y, Colletier JP, Weik M, Jiang H, Moult J, Silman I, Sussman JL. 2008. Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics. Biophysical journal 95(5): 2500-11. DOI: 10.1529/biophysj.108.129601
Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1.
Farina A, Shin JH, Kim DH, Bermudez VP, Kelman Z, Seo YS, Hurwitz J. 2008. Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1. The Journal of biological chemistry 283(30): 20925-36. DOI: 10.1074/jbc.M802696200