IBBR Publications

Found 23 results
Filters: Keyword is HIV Envelope Protein gp120  [Clear All Filters]
2015
Yang M, Mackerell AD. Conformational sampling of oligosaccharides using Hamiltonian replica exchange with two-dimensional dihedral biasing potentials and the weighted histogram analysis method (WHAM). J Chem Theory Comput. 2015 ;11(2):788-99.
Yang M, Huang J, Mackerell AD. Enhanced conformational sampling using replica exchange with concurrent solute scaling and hamiltonian biasing realized in one dimension. J Chem Theory Comput. 2015 ;11(6):2855-67.
2014
Pancera M, Zhou T, Druz A, Georgiev IS, Soto C, Gorman J, Huang J, Acharya P, Chuang G-Y, Ofek GA, et al. Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature. 2014 ;514(7523):455-61.
2012
Sundling C, Li Y, Huynh N, Poulsen C, Wilson R, O'Dell S, Feng Y, Mascola JR, Wyatt RT, Hedestam GBKarlsson. High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site. Sci Transl Med. 2012 ;4(142):142ra96.
Li Y, O'Dell S, Wilson R, Wu X, Schmidt SD, Hogerkorp C-M, Louder MK, Longo NS, Poulsen C, Guenaga J, et al. HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins. J Virol. 2012 ;86(20):11231-41.
Zhang M-Y, Yuan T, Li J, Borges ARosa, Watkins JD, Guenaga J, Yang Z, Wang Y, Wilson R, Li Y, et al. Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41. PLoS One. 2012 ;7(9):e44241.
Wu X, Wang C, O'Dell S, Li Y, Keele BF, Yang Z, Imamichi H, Doria-Rose N, Hoxie JA, Connors M, et al. Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site. J Virol. 2012 ;86(10):5844-56.
2011
Wang XXiang, Li Y, Yin Y, Mo M, Wang Q, Gao W, Wang L, Mariuzza RA. Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc Natl Acad Sci U S A. 2011 ;108(38):15960-5.
Li Y, O'Dell S, Walker LM, Wu X, Guenaga J, Feng Y, Schmidt SD, McKee K, Louder MK, Ledgerwood JE, et al. Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01. J Virol. 2011 ;85(17):8954-67.
2010
Stains CI, Furman JL, Porter JR, Rajagopal S, Li Y, Wyatt RT, Ghosh I. A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly. ACS Chem Biol. 2010 ;5(10):943-52.
Douagi I, Forsell MNE, Sundling C, O'Dell S, Feng Y, Dosenovic P, Li Y, Seder R, Loré K, Mascola JR, et al. Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates. J Virol. 2010 ;84(4):1683-95.
Wu X, Yang Z-Y, Li Y, Hogerkorp C-M, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science. 2010 ;329(5993):856-61.
2009
Li Y, Svehla K, Louder MK, Wycuff D, Phogat S, Tang M, Migueles SA, Wu X, Phogat A, Shaw GM, et al. Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals. J Virol. 2009 ;83(2):1045-59.
Scheid JF, Mouquet H, Feldhahn N, Seaman MS, Velinzon K, Pietzsch J, Ott RG, Anthony RM, Zebroski H, Hurley A, et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature. 2009 ;458(7238):636-40.
K Clark R, Walsh STR. Crystal structure of a 3B3 variant--a broadly neutralizing HIV-1 scFv antibody. Protein Sci. 2009 ;18(12):2429-41.
Dey B, Svehla K, Xu L, Wycuff D, Zhou T, Voss G, Phogat A, Chakrabarti BK, Li Y, Shaw G, et al. Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site. PLoS Pathog. 2009 ;5(5):e1000445.
2007
Dey B, Pancera M, Svehla K, Shu Y, Xiang S-H, Vainshtein J, Li Y, Sodroski J, Kwong PD, Mascola JR, et al. Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity. J Virol. 2007 ;81(11):5579-93.
2006
Li Y, Svehla K, Mathy NL, Voss G, Mascola JR, Wyatt R. Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants. J Virol. 2006 ;80(3):1414-26.
Zhu P, Liu J, Bess J, Chertova E, Lifson JD, Grisé H, Ofek GA, Taylor KA, Roux KH. Distribution and three-dimensional structure of AIDS virus envelope spikes. Nature. 2006 ;441(7095):847-52.
2005
Grundner C, Li Y, Louder M, Mascola J, Yang X, Sodroski J, Wyatt R. Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins. Virology. 2005 ;331(1):33-46.
Bleckwenn NA, Golding H, Bentley WE, Shiloach J. Production of recombinant proteins by vaccinia virus in a microcarrier based mammalian cell perfusion bioreactor. Biotechnol Bioeng. 2005 ;90(6):663-74.
Bleckwenn NA, Bentley WE, Shiloach J. Vaccinia virus-based expression of gp120 and EGFP: survey of mammalian host cell lines. Biotechnol Prog. 2005 ;21(1):186-91.
1998
Li H, Natarajan K, Malchiodi EL, Margulies DH, Mariuzza RA. Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120. J Mol Biol. 1998 ;283(1):179-91.