IBBR Publications
Found 44 results
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The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP. Biochemistry. 2017 ;56(17):2328-2337.
Acyl-2-aminobenzimidazoles: a novel class of neuroprotective agents targeting mGluR5. Bioorg Med Chem. 2015 ;23(9):2211-20.
. Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson's disease cell and mouse models. Hum Mol Genet. 2014 ;23(23):6212-22.
Enhancing biocompatibility of D-oligopeptide hydrogels by negative charges. Biomacromolecules. 2013 ;14(2):406-12.
. Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1. ACS Nano. 2012 ;6(10):8824-36.
. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature. 2012 ;491(7424):406-12.
A fibrinogen-derived peptide provides intercellular adhesion molecule-1-specific targeting and intraendothelial transport of polymer nanocarriers in human cell cultures and mice. J Pharmacol Exp Ther. 2012 ;340(3):638-47.
. HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins. J Virol. 2012 ;86(20):11231-41.
Identification of novel nonsteroidal compounds as substrates or inhibitors of hASBT. J Pharm Sci. 2012 ;101(1):116-26.
. Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium. Arterioscler Thromb Vasc Biol. 2012 ;32(5):1178-85.
. Protein stability and in vivo concentration of missense mutations in phenylalanine hydroxylase. Proteins. 2012 ;80(1):61-70.
. Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain. J Biol Chem. 2011 ;286(2):1189-95.
. Detecting protein interactions in live cells via complementation of a hydrolysis-deficient β-lactamase. Chem Commun (Camb). 2011 ;47(1):182-4.
. Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates. Mol Pharm. 2010 ;7(6):2240-54.
. Accumulation of large protein fragments in prematurely senescent ARPE-19 cells. Invest Ophthalmol Vis Sci. 2009 ;50(10):4992-7.
. Augmentation of Cav1 channel current and action potential duration after uptake of S100A1 in sympathetic ganglion neurons. Am J Physiol Cell Physiol. 2009 ;297(4):C955-70.
. The Qgamma component of intra-membrane charge movement is present in mammalian muscle fibres, but suppressed in the absence of S100A1. J Physiol. 2009 ;587(Pt 18):4523-41.
. Simultaneous recording of intramembrane charge movement components and calcium release in wild-type and S100A1-/- muscle fibres. J Physiol. 2009 ;587(Pt 18):4543-59.
. Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes. J Control Release. 2008 ;130(3):226-33.
. Identification and validation of human DNA ligase inhibitors using computer-aided drug design. J Med Chem. 2008 ;51(15):4553-62.
. Oxygen microscopy by two-photon-excited phosphorescence. Chemphyschem. 2008 ;9(12):1673-9.
. . Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at alpha7* nicotinic receptors. J Pharmacol Exp Ther. 2007 ;322(1):48-58.
. Engineering eukaryotic signal transduction with RNAi: enhancing Drosophila S2 cell growth and recombinant protein synthesis via silencing of TSC1. Biotechnol Bioeng. 2006 ;95(4):645-52.
. Lysosomal enzyme delivery by ICAM-1-targeted nanocarriers bypassing glycosylation- and clathrin-dependent endocytosis. Mol Ther. 2006 ;13(1):135-41.
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