IBBR Publications
Found 172 results
Filters: Keyword is Protein Structure, Tertiary [Clear All Filters]
Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain. Proc Natl Acad Sci U S A. 2015 ;112(17):5455-60.
Insight into Early-Stage Unfolding of GPI-Anchored Human Prion Protein. Biophys J. 2015 ;109(10):2090-100.
. Quantifying the Binding Interaction between the Hypoxia-Inducible Transcription Factor and the von Hippel-Lindau Suppressor. J Chem Theory Comput. 2015 ;11(8):3946-54.
. Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies. Proc Natl Acad Sci U S A. 2014 ;111(18):6714-9.
Internal lipid architecture of the hetero-oligomeric cytochrome b6f complex. Structure. 2014 ;22(7):1008-15.
. A map of dielectric heterogeneity in a membrane protein: the hetero-oligomeric cytochrome b6f complex. J Phys Chem B. 2014 ;118(24):6614-25.
. Calcitriol-induced DNA damage: toward a molecular mechanism of selective cell death. IUBMB Life. 2013 ;65(9):787-92.
. Hsp70 is a novel posttranscriptional regulator of gene expression that binds and stabilizes selected mRNAs containing AU-rich elements. Mol Cell Biol. 2013 ;33(1):71-84.
. Lipid-induced conformational changes within the cytochrome b6f complex of oxygenic photosynthesis. Biochemistry. 2013 ;52(15):2649-54.
. The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak. Mol Cancer. 2013 ;12(1):42.
Quinone-dependent proton transfer pathways in the photosynthetic cytochrome b6f complex. Proc Natl Acad Sci U S A. 2013 ;110(11):4297-302.
. Structural and functional analysis of the pro-domain of human cathelicidin, LL-37. Biochemistry. 2013 ;52(9):1547-58.
Transmembrane domain II of the human bile acid transporter SLC10A2 coordinates sodium translocation. J Biol Chem. 2013 ;288(45):32394-404.
. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature. 2012 ;491(7424):406-12.
Crystal structure of the Sema-PSI extracellular domain of human RON receptor tyrosine kinase. PLoS One. 2012 ;7(7):e41912.
. DNA binding specificity of ATAF2, a NAC domain transcription factor targeted for degradation by Tobacco mosaic virus. BMC Plant Biol. 2012 ;12:157.
. Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA. Proc Natl Acad Sci U S A. 2012 ;109(21):8091-6.
. Lipid functions in cytochrome bc complexes: an odd evolutionary transition in a membrane protein structure. Philos Trans R Soc Lond B Biol Sci. 2012 ;367(1608):3406-11.
. Mutational tipping points for switching protein folds and functions. Structure. 2012 ;20(2):283-91.
. Protein stability and in vivo concentration of missense mutations in phenylalanine hydroxylase. Proteins. 2012 ;80(1):61-70.
. Putative irreversible inhibitors of the human sodium-dependent bile acid transporter (hASBT; SLC10A2) support the role of transmembrane domain 7 in substrate binding/translocation. Pharm Res. 2012 ;29(7):1821-31.
. Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors. Org Biomol Chem. 2012 ;10(15):2928-33.
. Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum. Proteins. 2012 ;80(12):2810-7.
. X-ray crystal structure of the streptococcal specific phage lysin PlyC. Proc Natl Acad Sci U S A. 2012 ;109(31):12752-7.
Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc Natl Acad Sci U S A. 2011 ;108(38):15960-5.
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