IBBR Publications
Found 257 results
Filters: Keyword is Binding Sites [Clear All Filters]
The structural and biochemical impacts of monomerizing human acetylcholinesterase. Protein Sci. 2019 ;28(6):1106-1114.
Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep. 2018 ;25(11):3136-3147.e5.
A human antibody against Zika virus crosslinks the E protein to prevent infection. Nat Commun. 2017 ;8:14722.
Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme Activity. J Biol Chem. 2016 ;291(22):11876-86.
. Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators. Chem Commun (Camb). 2015 ;51(13):2617-20.
. Mapping functional group free energy patterns at protein occluded sites: nuclear receptors and G-protein coupled receptors. J Chem Inf Model. 2015 ;55(3):700-8.
. Spatial analysis and quantification of the thermodynamic driving forces in protein-ligand binding: binding site variability. J Am Chem Soc. 2015 ;137(7):2608-21.
. Internal lipid architecture of the hetero-oligomeric cytochrome b6f complex. Structure. 2014 ;22(7):1008-15.
. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc Natl Acad Sci U S A. 2014 ;111(7):E738-47.
Factorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium. Nucleic Acids Res. 2013 ;41(Database issue):D171-6.
Hsp70 is a novel posttranscriptional regulator of gene expression that binds and stabilizes selected mRNAs containing AU-rich elements. Mol Cell Biol. 2013 ;33(1):71-84.
. Impact of substrate protonation and tautomerization states on interactions with the active site of arginase I. J Chem Inf Model. 2013 ;53(2):452-60.
. Balancing target flexibility and target denaturation in computational fragment-based inhibitor discovery. J Comput Chem. 2012 ;33(23):1880-91.
. Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA. J Mol Biol. 2012 ;420(3):164-75.
. Effect of thiol pendant conjugates on plasmid DNA binding, release, and stability of polymeric delivery vectors. Biomacromolecules. 2012 ;13(5):1331-9.
. Exploring the DNA-recognition potential of homeodomains. Genome Res. 2012 ;22(10):1889-98.
. High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site. Sci Transl Med. 2012 ;4(142):142ra96.
. Hydrophobic residues in small ankyrin 1 participate in binding to obscurin. Mol Membr Biol. 2012 ;29(2):36-51.
. Lipid functions in cytochrome bc complexes: an odd evolutionary transition in a membrane protein structure. Philos Trans R Soc Lond B Biol Sci. 2012 ;367(1608):3406-11.
. Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors. Org Biomol Chem. 2012 ;10(15):2928-33.
. Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site. J Virol. 2012 ;86(10):5844-56.
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. Genome Res. 2012 ;22(9):1798-812.
Structural basis for self-recognition by autoimmune T-cell receptors. Immunol Rev. 2012 ;250(1):32-48.
. Structural insights into the common γ-chain family of cytokines and receptors from the interleukin-7 pathway. Immunol Rev. 2012 ;250(1):303-16.
. Structure of aminodeoxychorismate synthase from Stenotrophomonas maltophilia. Biochemistry. 2012 ;51(51):10208-17.
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