IBBR Publications
Found 62 results
Filters: Keyword is Substrate Specificity [Clear All Filters]
Characterization of AlgMsp, an alginate lyase from Microbulbifer sp. 6532A. PLoS One. 2014 ;9(11):e112939.
. Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies. Proc Natl Acad Sci U S A. 2014 ;111(18):6714-9.
Impact of substrate protonation and tautomerization states on interactions with the active site of arginase I. J Chem Inf Model. 2013 ;53(2):452-60.
. Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA. J Mol Biol. 2012 ;420(3):164-75.
. Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA. Proc Natl Acad Sci U S A. 2012 ;109(21):8091-6.
. Structure and activity of PA5508, a hexameric glutamine synthetase homologue. Biochemistry. 2012 ;51(51):10121-3.
. Active-site structure of class IV adenylyl cyclase and transphyletic mechanism. J Mol Biol. 2011 ;405(3):787-803.
. Conversion of 7-ketocholesterol to oxysterol metabolites by recombinant CYP27A1 and retinal pigment epithelial cells. J Lipid Res. 2011 ;52(6):1117-27.
. Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member. Biochemistry. 2010 ;49(9):2031-41.
. Structure of oxalacetate acetylhydrolase, a virulence factor of the chestnut blight fungus. J Biol Chem. 2010 ;285(34):26685-96.
. Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase. Structure. 2010 ;18(4):494-506.
. Unique properties of the Mtr4p-poly(A) complex suggest a role in substrate targeting. Biochemistry. 2010 ;49(49):10357-70.
. Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase. Biochemistry. 2009 ;48(28):6559-61.
. Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase. Arch Biochem Biophys. 2009 ;483(1):81-9.
. Oligo(ethylene oxide) self-assembled monolayers with self-limiting packing densities for the inhibition of nonspecific protein adsorption. Langmuir. 2009 ;25(9):5026-30.
. Steroid and protein ligand binding to cytochrome P450 46A1 as assessed by hydrogen-deuterium exchange and mass spectrometry. Biochemistry. 2009 ;48(19):4150-8.
. Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase. Biochemistry. 2009 ;48(14):3186-96.
. Structure and function of 2,3-dimethylmalate lyase, a PEP mutase/isocitrate lyase superfamily member. J Mol Biol. 2009 ;386(2):486-503.
. Structure of PqsD, a Pseudomonas quinolone signal biosynthetic enzyme, in complex with anthranilate. Biochemistry. 2009 ;48(36):8644-55.
. Characterization of the essential activities of Saccharomyces cerevisiae Mtr4p, a 3'->5' helicase partner of the nuclear exosome. J Biol Chem. 2008 ;283(8):4930-42.
. Crystal structure of the pyocyanin biosynthetic protein PhzS. Biochemistry. 2008 ;47(19):5281-9.
. Engineering substrate preference in subtilisin: structural and kinetic analysis of a specificity mutant. Biochemistry. 2008 ;47(25):6628-36.
. Identification and validation of human DNA ligase inhibitors using computer-aided drug design. J Med Chem. 2008 ;51(15):4553-62.
. A new nitrilase from Bradyrhizobium japonicum USDA 110. Gene cloning, biochemical characterization and substrate specificity. J Biotechnol. 2008 ;133(3):327-33.
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