IBBR Publications

Found 62 results
Filters: Keyword is Substrate Specificity  [Clear All Filters]
2014
Swift SM, Hudgens JW, Heselpoth RD, Bales PM, Nelson DC. Characterization of AlgMsp, an alginate lyase from Microbulbifer sp. 6532A. PLoS One. 2014 ;9(11):e112939.
Trastoy B, Lomino JV, Pierce BG, Carter LG, Günther S, Giddens JP, Snyder GA, Weiss TM, Weng Z, Wang L-X, et al. Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies. Proc Natl Acad Sci U S A. 2014 ;111(18):6714-9.
2013
Nagagarajan S, Xue F, Mackerell AD. Impact of substrate protonation and tautomerization states on interactions with the active site of arginase I. J Chem Inf Model. 2013 ;53(2):452-60.
2012
Manvilla BA, Maiti A, Begley MC, Toth EA, Drohat AC. Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA. J Mol Biol. 2012 ;420(3):164-75.
Maiti A, Noon MS, Mackerell AD, Pozharski E, Drohat AC. Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA. Proc Natl Acad Sci U S A. 2012 ;109(21):8091-6.
Ladner JE, Atanasova V, Dolezelova Z, Parsons JF. Structure and activity of PA5508, a hexameric glutamine synthetase homologue. Biochemistry. 2012 ;51(51):10121-3.
2011
D Gallagher T, Kim S-K, Robinson H, Reddy PT. Active-site structure of class IV adenylyl cyclase and transphyletic mechanism. J Mol Biol. 2011 ;405(3):787-803.
Heo G-Y, Bederman I, Mast N, Liao W-L, Turko IV, Pikuleva IA. Conversion of 7-ketocholesterol to oxysterol metabolites by recombinant CYP27A1 and retinal pigment epithelial cells. J Lipid Res. 2011 ;52(6):1117-27.
2010
Lim K, Pullalarevu S, Surabian KTalin, Howard A, Suzuki T, Moult J, Herzberg O. Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member. Biochemistry. 2010 ;49(9):2031-41.
Chen C, Sun Q, Narayanan B, Nuss DL, Herzberg O. Structure of oxalacetate acetylhydrolase, a virulence factor of the chestnut blight fungus. J Biol Chem. 2010 ;285(34):26685-96.
Mittag T, Marsh J, Grishaev A, Orlicky S, Lin H, Sicheri F, Tyers M, Forman-Kay JD. Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase. Structure. 2010 ;18(4):494-506.
Bernstein J, Ballin JD, Patterson DN, Wilson GM, Toth EA. Unique properties of the Mtr4p-poly(A) complex suggest a role in substrate targeting. Biochemistry. 2010 ;49(49):10357-70.
2009
Wadington MC, Ladner JE, Stourman NV, Harp JM, Armstrong RN. Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase. Biochemistry. 2009 ;48(28):6559-61.
Mast N, Liao W-L, Pikuleva IA, Turko IV. Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase. Arch Biochem Biophys. 2009 ;483(1):81-9.
Vanderah DJ, Vierling RJ, Walker ML. Oligo(ethylene oxide) self-assembled monolayers with self-limiting packing densities for the inhibition of nonspecific protein adsorption. Langmuir. 2009 ;25(9):5026-30.
Liao W-L, Dodder NG, Mast N, Pikuleva IA, Turko IV. Steroid and protein ligand binding to cytochrome P450 46A1 as assessed by hydrogen-deuterium exchange and mass spectrometry. Biochemistry. 2009 ;48(19):4150-8.
Galkin A, Li Z, Li L, Kulakova L, Pal LR, Dunaway-Mariano D, Herzberg O. Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase. Biochemistry. 2009 ;48(14):3186-96.
Narayanan B, Niu W, Joosten H-J, Li Z, Kuipers RKP, Schaap PJ, Dunaway-Mariano D, Herzberg O. Structure and function of 2,3-dimethylmalate lyase, a PEP mutase/isocitrate lyase superfamily member. J Mol Biol. 2009 ;386(2):486-503.
Bera AK, Atanasova V, Robinson H, Eisenstein E, Coleman JP, Pesci EC, Parsons JF. Structure of PqsD, a Pseudomonas quinolone signal biosynthetic enzyme, in complex with anthranilate. Biochemistry. 2009 ;48(36):8644-55.
2008
Bernstein J, Patterson DN, Wilson GM, Toth EA. Characterization of the essential activities of Saccharomyces cerevisiae Mtr4p, a 3'->5' helicase partner of the nuclear exosome. J Biol Chem. 2008 ;283(8):4930-42.
Greenhagen BT, Shi K, Robinson H, Gamage S, Bera AK, Ladner JE, Parsons JF. Crystal structure of the pyocyanin biosynthetic protein PhzS. Biochemistry. 2008 ;47(19):5281-9.
Ruan B, London V, Fisher KE, D Gallagher T, Bryan PN. Engineering substrate preference in subtilisin: structural and kinetic analysis of a specificity mutant. Biochemistry. 2008 ;47(25):6628-36.
Zhong S, Chen X, Zhu X, Dziegielewska B, Bachman KE, Ellenberger T, Ballin JD, Wilson GM, Tomkinson AE, Mackerell AD. Identification and validation of human DNA ligase inhibitors using computer-aided drug design. J Med Chem. 2008 ;51(15):4553-62.
Zhu D, Mukherjee C, Yang Y, Rios BE, D Gallagher T, N Smith N, Biehl ER, Hua L. A new nitrilase from Bradyrhizobium japonicum USDA 110. Gene cloning, biochemical characterization and substrate specificity. J Biotechnol. 2008 ;133(3):327-33.
Narayanan BC, Niu W, Han Y, Zou J, Mariano PS, Dunaway-Mariano D, Herzberg O. Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily. Biochemistry. 2008 ;47(1):167-82.