Found 11 results
Filters: Keyword is HIV-1 and Author is Wyatt, Richard T [Clear All Filters]
Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization. J Immunol. 2014 ;192(8):3637-44..
Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc Natl Acad Sci U S A. 2014 ;111(7):E738-47.
High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site. Sci Transl Med. 2012 ;4(142):142ra96..
HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins. J Virol. 2012 ;86(20):11231-41.
Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site. J Virol. 2012 ;86(10):5844-56.
Heterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant. PLoS One. 2011 ;6(1):e16074..
Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01. J Virol. 2011 ;85(17):8954-67.
A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly. ACS Chem Biol. 2010 ;5(10):943-52..
Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates. J Virol. 2010 ;84(4):1683-95.
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science. 2010 ;329(5993):856-61.
Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nat Med. 2007 ;13(9):1032-4.