Publications

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PCPP-Adjuvanted Respiratory Syncytial Virus (RSV) sF Subunit Vaccine: Self-Assembled Supramolecular Complexes Enable Enhanced Immunogenicity and Protection.
Cayatte C, Marin A, Rajani GM, Schneider-Ohrum K, Snell Bennett A, Marshall JD, Andrianov AK. 2017. PCPP-Adjuvanted Respiratory Syncytial Virus (RSV) sF Subunit Vaccine: Self-Assembled Supramolecular Complexes Enable Enhanced Immunogenicity and Protection. Molecular pharmaceutics 14(7): 2285-2293. DOI: 10.1021/acs.molpharmaceut.7b00118
Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges.
Cai B, Li B, Kiga N, Thusberg J, Bergquist T, Chen YC, Niknafs N, Carter H, Tokheim C, Beleva-Guthrie V, et al. 2017. Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges. Human mutation 38(9): 1266-1276. DOI: 10.1002/humu.23265
Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges.
Yin Y, Kundu K, Pal LR, Moult J. 2017. Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges. Human mutation 38(9): 1109-1122. DOI: 10.1002/humu.23267
Biodegradable "Smart" Polyphosphazenes with Intrinsic Multifunctionality as Intracellular Protein Delivery Vehicles.
Martinez AP, Qamar B, Fuerst TR, Muro S, Andrianov AK. 2017. Biodegradable "Smart" Polyphosphazenes with Intrinsic Multifunctionality as Intracellular Protein Delivery Vehicles. Biomacromolecules 18(6): 2000-2011. DOI: 10.1021/acs.biomac.7b00537
Biofabrication of Tobacco mosaic virus-nanoscaffolded supercapacitors via temporal capillary microfluidics.
Zang F, Chu S, Gerasopoulos K, Culver JN, Ghodssi R. 2017. Biofabrication of Tobacco mosaic virus-nanoscaffolded supercapacitors via temporal capillary microfluidics. Nanotechnology 28(26): 265301. DOI: 10.1088/1361-6528/aa742f
Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.
Zhao X, Howell KA, He S, Brannan JM, Wec AZ, Davidson E, Turner HL, Chiang CI, Lei L, Fels JM, et al. 2017. Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell 169(5): 891-904.e15. DOI: 10.1016/j.cell.2017.04.038
CAGI4 Crohn's exome challenge: Marker SNP versus exome variant models for assigning risk of Crohn disease.
Pal LR, Kundu K, Yin Y, Moult J. 2017. CAGI4 Crohn's exome challenge: Marker SNP versus exome variant models for assigning risk of Crohn disease. Human mutation 38(9): 1225-1234. DOI: 10.1002/humu.23256
CAGI4 SickKids clinical genomes challenge: A pipeline for identifying pathogenic variants.
Pal LR, Kundu K, Yin Y, Moult J. 2017. CAGI4 SickKids clinical genomes challenge: A pipeline for identifying pathogenic variants. Human mutation 38(9): 1169-1181. DOI: 10.1002/humu.23257
Lysosomal enzyme replacement therapies: Historical development, clinical outcomes, and future perspectives.
Solomon M, Muro S. 2017. Lysosomal enzyme replacement therapies: Historical development, clinical outcomes, and future perspectives. Advanced drug delivery reviews 118: 109-134. DOI: 10.1016/j.addr.2017.05.004
Determination of disease phenotypes and pathogenic variants from exome sequence data in the CAGI 4 gene panel challenge.
Kundu K, Pal LR, Yin Y, Moult J. 2017. Determination of disease phenotypes and pathogenic variants from exome sequence data in the CAGI 4 gene panel challenge. Human mutation 38(9): 1201-1216. DOI: 10.1002/humu.23249
Conformational Changes in Active and Inactive States of Human PP2Cα Characterized by Hydrogen/Deuterium Exchange-Mass Spectrometry.
Mazur SJ, Gallagher ES, Debnath S, Durell SR, Anderson KW, Miller Jenkins LM, Appella E, Hudgens JW. 2017. Conformational Changes in Active and Inactive States of Human PP2Cα Characterized by Hydrogen/Deuterium Exchange-Mass Spectrometry. Biochemistry 56(21): 2676-2689. DOI: 10.1021/acs.biochem.6b01220
Molecular processes in an electrochemical clozapine sensor.
Winkler TE, Lederer SL, Kim E, Ben-Yoav H, Kelly DL, Payne GF, Ghodssi R. 2017. Molecular processes in an electrochemical clozapine sensor. Biointerphases 12(2): 02B401. DOI: 10.1116/1.4982709
Application of 2D-NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim.
Brinson RG, Ghasriani H, Hodgson DJ, Adams KM, McEwen I, Freedberg DI, Chen K, Keire DA, Aubin Y, Marino JP. 2017. Application of 2D-NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim. Journal of pharmaceutical and biomedical analysis 141: 229-233. DOI: 10.1016/j.jpba.2017.03.063
NMRbox: A Resource for Biomolecular NMR Computation.
Maciejewski MW, Schuyler AD, Gryk MR, Moraru II, Romero PR, Ulrich EL, Eghbalnia HR, Livny M, Delaglio F, Hoch JC. 2017. NMRbox: A Resource for Biomolecular NMR Computation. Biophysical journal 112(8): 1529-1534. DOI: 10.1016/j.bpj.2017.03.011
Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI.
Carraro M, Minervini G, Giollo M, Bromberg Y, Capriotti E, Casadio R, Dunbrack R, Elefanti L, Fariselli P, Ferrari C, et al. 2017. Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI. Human mutation 38(9): 1042-1050. DOI: 10.1002/humu.23235