IBBR Publications

Found 9 results
Filters: Author is Alexander, Patrick A  [Clear All Filters]
2012
He Y, Chen Y, Alexander PA, Bryan PN, Orban J. Mutational tipping points for switching protein folds and functions. Structure. 2012 ;20(2):283-91.
2009
Alexander PA, He Y, Chen Y, Orban J, Bryan PN. A minimal sequence code for switching protein structure and function. Proc Natl Acad Sci U S A. 2009 ;106(50):21149-54.
2007
Alexander PA, He Y, Chen Y, Orban J, Bryan PN. The design and characterization of two proteins with 88% sequence identity but different structure and function. Proc Natl Acad Sci U S A. 2007 ;104(29):11963-8.
Sari N, Ruan B, Fisher KE, Alexander PA, Orban J, Bryan PN. Hydrogen-deuterium exchange in free and prodomain-complexed subtilisin. Biochemistry. 2007 ;46(3):652-8.
Fisher KE, Ruan B, Alexander PA, Wang L, Bryan PN. Mechanism of the kinetically-controlled folding reaction of subtilisin. Biochemistry. 2007 ;46(3):640-51.
2006
Rozak DA, Alexander PA, He Y, Chen Y, Orban J, Bryan PN. Using offset recombinant polymerase chain reaction to identify functional determinants in a common family of bacterial albumin binding domains. Biochemistry. 2006 ;45(10):3263-71.
2005
Strausberg SL, Ruan B, Fisher KE, Alexander PA, Bryan PN. Directed coevolution of stability and catalytic activity in calcium-free subtilisin. Biochemistry. 2005 ;44(9):3272-9.
Alexander PA, Rozak DA, Orban J, Bryan PN. Directed evolution of highly homologous proteins with different folds by phage display: implications for the protein folding code. Biochemistry. 2005 ;44(43):14045-54.
2004
Ruan B, Fisher KE, Alexander PA, Doroshko V, Bryan PN. Engineering subtilisin into a fluoride-triggered processing protease useful for one-step protein purification. Biochemistry. 2004 ;43(46):14539-46.