Publications

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Creation and filtering of a recurrent spectral library of CHO cell metabolites and media components.
Telu KH, Marupaka R, Andriamaharavo NR, Simón-Manso Y, Liang Y, Mirokhin YA, Bukhari TH, Preston RJ, Kashi L, Kelman Z, et al. 2021. Creation and filtering of a recurrent spectral library of CHO cell metabolites and media components. Biotechnology and bioengineering 118(4): 1491-1510. DOI: 10.1002/bit.27661
Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint.
Solano-Gonzalez E, Coburn KM, Yu W, Wilson GM, Nurmemmedov E, Kesari S, Chang ET, MacKerell AD, Weber DJ, Carrier F. 2021. Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint. Nucleic acids research 49(3): 1235-1246. DOI: 10.1093/nar/gkaa1254
High-throughput modeling and scoring of TCR-pMHC complexes to predict cross-reactive peptides.
Borrman T, Pierce BG, Vreven T, Baker BM, Weng Z. 2020. High-throughput modeling and scoring of TCR-pMHC complexes to predict cross-reactive peptides. Bioinformatics (Oxford, England) : . DOI: 10.1093/bioinformatics/btaa1050
Structural Characterization and Modeling of a Respiratory Syncytial Virus Fusion Glycoprotein Nanoparticle Vaccine in Solution.
Krueger S, Curtis JE, Scott DR, Grishaev A, Glenn G, Smith G, Ellingsworth L, Borisov O, Maynard EL. 2021. Structural Characterization and Modeling of a Respiratory Syncytial Virus Fusion Glycoprotein Nanoparticle Vaccine in Solution. Molecular pharmaceutics 18(1): 359-376. DOI: 10.1021/acs.molpharmaceut.0c00986
Polyphosphazenes enable durable, hemocompatible, highly efficient antibacterial coatings.
Albright V, Penarete-Acosta D, Stack M, Zheng J, Marin A, Hlushko H, Wang H, Jayaraman A, Andrianov AK, Sukhishvili SA. 2021. Polyphosphazenes enable durable, hemocompatible, highly efficient antibacterial coatings. Biomaterials 268: 120586. DOI: 10.1016/j.biomaterials.2020.120586
Sand Fly (Phlebotomus papatasi) Embryo Microinjection for CRISPR/Cas9 Mutagenesis.
Louradour I, Ghosh K, Inbar E, Sacks DL, Aluvihare C, Harrell RA. 2020. Sand Fly (Phlebotomus papatasi) Embryo Microinjection for CRISPR/Cas9 Mutagenesis. Journal of visualized experiments : JoVE (165): . DOI: 10.3791/61924
Polyphosphazene immunoadjuvants: Historical perspective and recent advances.
Andrianov AK, Langer R. 2021. Polyphosphazene immunoadjuvants: Historical perspective and recent advances. Journal of controlled release : official journal of the Controlled Release Society 329: 299-315. DOI: 10.1016/j.jconrel.2020.12.001
Sequencing and analysis of gerbera daisy leaf transcriptomes reveal disease resistance and susceptibility genes differentially expressed and associated with powdery mildew resistance.
Bhattarai K, Conesa A, Xiao S, Peres NA, Clark DG, Parajuli S, Deng Z. 2020. Sequencing and analysis of gerbera daisy leaf transcriptomes reveal disease resistance and susceptibility genes differentially expressed and associated with powdery mildew resistance. BMC plant biology 20(1): 539. DOI: 10.1186/s12870-020-02742-4
Crystal Structure of a Bivalent Antibody Fab Fragment.
Shahid S, Gao M, Travis Gallagher D, Pozharski E, Brinson RG, Keck ZY, Foung SKH, Fuerst TR, Mariuzza RA. 2021. Crystal Structure of a Bivalent Antibody Fab Fragment. Journal of molecular biology 433(2): 166714. DOI: 10.1016/j.jmb.2020.11.013
Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo.
Maranto C, Udhane V, Jia J, Verma R, Müller-Newen G, LaViolette PS, Pereckas M, Sabharwal L, Terhune S, Pattabiraman N, et al. 2020. Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo. Cancers 12(11): . DOI: 10.3390/cancers12113412
The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses.
Weston S, Baracco L, Keller C, Matthews K, McGrath ME, Logue J, Liang J, Dyall J, Holbrook MR, Hensley LE, et al. 2020. The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses. Proceedings of the National Academy of Sciences of the United States of America 117(48): 30687-30698. DOI: 10.1073/pnas.2012939117
Quantitative Proteomic Analysis of Biogenesis-Based Classification for Extracellular Vesicles.
Zhang L, Parot J, Hackley VA, Turko IV. 2020. Quantitative Proteomic Analysis of Biogenesis-Based Classification for Extracellular Vesicles. Proteomes 8(4): . DOI: 10.3390/proteomes8040033
COVID-19 reopening strategies at the county level in the face of uncertainty: Multiple Models for Outbreak Decision Support.
Shea K, Borchering RK, Probert WJM, Howerton E, Bogich TL, Li S, van Panhuis WG, Viboud C, Aguás R, Belov A, et al. 2020. COVID-19 reopening strategies at the county level in the face of uncertainty: Multiple Models for Outbreak Decision Support. medRxiv : the preprint server for health sciences : . DOI: 10.1101/2020.11.03.20225409
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, et al. 2020. An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science (New York, N.Y.) 370(6523): 1473-1479. DOI: 10.1126/science.abe3255
Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs).
He Y, Agnihotri P, Rangarajan S, Chen Y, Kerzic MC, Ma B, Nussinov R, Mariuzza RA, Orban J. 2020. Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs). Journal of molecular biology 432(24): 166697. DOI: 10.1016/j.jmb.2020.10.031