Publications

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Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation.
Austin JW, Buckner CM, Kardava L, Wang W, Zhang X, Melson VA, Swanson RG, Martins AJ, Zhou JQ, Hoehn KB, et al. 2019. Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation. Science translational medicine 11(520): . DOI: 10.1126/scitranslmed.aax0904
Linker Editing of Pneumococcal Lysin ClyJ Conveys Improved Bactericidal Activity.
Yang H, Luo D, Etobayeva I, Li X, Gong Y, Wang S, Li Q, Xu P, Yin W, He J, et al. 2020. Linker Editing of Pneumococcal Lysin ClyJ Conveys Improved Bactericidal Activity. Antimicrobial agents and chemotherapy 64(2): . DOI: 10.1128/AAC.01610-19
Protein-loaded soluble and nanoparticulate formulations of ionic polyphosphazenes and their interactions on molecular and cellular levels.
Andrianov AK, Marin A, Deng J, Fuerst TR. 2020. Protein-loaded soluble and nanoparticulate formulations of ionic polyphosphazenes and their interactions on molecular and cellular levels. Materials science & engineering. C, Materials for biological applications 106: 110179. DOI: 10.1016/j.msec.2019.110179
Hydrophobicity and oligomerization are essential parameters for membrane penetration activity of the VP4 peptide from Hepatitis A Virus (HAV).
Nair P, Dey D, Borkotoky S, Shukla A, Banerjee M. 2019. Hydrophobicity and oligomerization are essential parameters for membrane penetration activity of the VP4 peptide from Hepatitis A Virus (HAV). Archives of biochemistry and biophysics 678: 108188. DOI: 10.1016/j.abb.2019.108188
Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
Phad GE, Pushparaj P, Tran K, Dubrovskaya V, Àdori M, Martinez-Murillo P, Vázquez Bernat N, Singh S, Dionne G, O'Dell S, et al. 2020. Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. The Journal of experimental medicine 217(2): . DOI: 10.1084/jem.20191155
Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
Pidugu LS, Dai Q, Malik SS, Pozharski E, Drohat AC. 2019. Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase. Journal of the American Chemical Society 141(47): 18851-18861. DOI: 10.1021/jacs.9b10376
Strategies for Development of a Next-Generation Protein Sequencing Platform.
Callahan N, Tullman J, Kelman Z, Marino J. 2020. Strategies for Development of a Next-Generation Protein Sequencing Platform. Trends in biochemical sciences 45(1): 76-89. DOI: 10.1016/j.tibs.2019.09.005
Matching whole genomes to rare genetic disorders: Identification of potential causative variants using phenotype-weighted knowledge in the CAGI SickKids5 clinical genomes challenge.
Pal LR, Kundu K, Yin Y, Moult J. 2020. Matching whole genomes to rare genetic disorders: Identification of potential causative variants using phenotype-weighted knowledge in the CAGI SickKids5 clinical genomes challenge. Human mutation 41(2): 347-362. DOI: 10.1002/humu.23933
Galeterone and The Next Generation Galeterone Analogs, VNPP414 and VNPP433-3β Exert Potent Therapeutic Effects in Castration-/Drug-Resistant Prostate Cancer Preclinical Models In Vitro and In Vivo.
Kwegyir-Afful AK, Ramalingam S, Ramamurthy VP, Purushottamachar P, Murigi FN, Vasaitis TS, Huang W, Kane MA, Zhang Y, Ambulos N, et al. 2019. Galeterone and The Next Generation Galeterone Analogs, VNPP414 and VNPP433-3β Exert Potent Therapeutic Effects in Castration-/Drug-Resistant Prostate Cancer Preclinical Models In Vitro and In Vivo. Cancers 11(11): . DOI: 10.3390/cancers11111637
Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions.
Gallagher DT, McCullough C, Brinson RG, Ahn J, Marino JP, Dimasi N. 2019. Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions. Pharmaceutics 11(10): . DOI: 10.3390/pharmaceutics11100546
The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels.
Comert F, Greenwood A, Maramba J, Acevedo R, Lucas L, Kulasinghe T, Cairns LS, Wen Y, Fu R, Hammer J, et al. 2019. The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels. The Journal of biological chemistry 294(49): 18557-18570. DOI: 10.1074/jbc.RA119.010232
Blind prediction of homo- and hetero-protein complexes: The CASP13-CAPRI experiment.
Lensink MF, Brysbaert G, Nadzirin N, Velankar S, Chaleil RAG, Gerguri T, Bates PA, Laine E, Carbone A, Grudinin S, et al. 2019. Blind prediction of homo- and hetero-protein complexes: The CASP13-CAPRI experiment. Proteins 87(12): 1200-1221. DOI: 10.1002/prot.25838
Characterization of the internal translation initiation region in monoclonal antibodies expressed in Escherichia coli.
Leith EM, O'Dell WB, Ke N, McClung C, Berkmen M, Bergonzo C, Brinson RG, Kelman Z. 2019. Characterization of the internal translation initiation region in monoclonal antibodies expressed in <i>Escherichia coli</i>. The Journal of biological chemistry 294(48): 18046-18056. DOI: 10.1074/jbc.RA119.011008
Critical assessment of methods of protein structure prediction (CASP)-Round XIII.
Kryshtafovych A, Schwede T, Topf M, Fidelis K, Moult J. 2019. Critical assessment of methods of protein structure prediction (CASP)-Round XIII. Proteins 87(12): 1011-1020. DOI: 10.1002/prot.25823
Geometrical characterization of T cell receptor binding modes reveals class-specific binding to maximize access to antigen.
Singh NK, Abualrous ET, Ayres CM, Noé F, Gowthaman R, Pierce BG, Baker BM. 2020. Geometrical characterization of T cell receptor binding modes reveals class-specific binding to maximize access to antigen. Proteins 88(3): 503-513. DOI: 10.1002/prot.25829