IBBR Publications

Found 10 results
Filters: Author is Heselpoth, Ryan D  [Clear All Filters]
2019
Greenfield J, Shang X, Luo H, Zhou Y, Heselpoth RD, Nelson DC, Herzberg O. Structure and tailspike glycosidase machinery of ORF212 from E. coli O157:H7 phage CBA120 (TSP3). Sci Rep. 2019 ;9(1):7349.
2016
Shen Y, Barros M, Vennemann T, D Gallagher T, Yin Y, Linden SB, Heselpoth RD, Spencer DJ, Donovan DM, Moult J, et al. A bacteriophage endolysin that eliminates intracellular streptococci. Elife. 2016 ;5.
Yang X, Lin Y-P, Heselpoth RD, Buyuktanir O, Qin J, Kung F, Nelson DC, Leong JM, Pal U. Middle region of the Borrelia burgdorferi surface-located protein 1 (Lmp1) interacts with host chondroitin-6-sulfate and independently facilitates infection. Cell Microbiol. 2016 ;18(1):97-110.
2015
Heselpoth RD, Yin Y, Moult J, Nelson DC. Increasing the stability of the bacteriophage endolysin PlyC using rationale-based FoldX computational modeling. Protein Eng Des Sel. 2015 ;28(4):85-92.
2014
Linden SB, Zhang H, Heselpoth RD, Shen Y, Schmelcher M, Eichenseher F, Nelson DC. Biochemical and biophysical characterization of PlyGRCS, a bacteriophage endolysin active against methicillin-resistant Staphylococcus aureus. Appl Microbiol Biotechnol. 2014 .
Swift SM, Hudgens JW, Heselpoth RD, Bales PM, Nelson DC. Characterization of AlgMsp, an alginate lyase from Microbulbifer sp. 6532A. PLoS One. 2014 ;9(11):e112939.
Chen C, Bales P, Greenfield J, Heselpoth RD, Nelson DC, Herzberg O. Crystal Structure of ORF210 from E. coli O157:H1 Phage CBA120 (TSP1), a Putative Tailspike Protein. PLoS One. 2014 ;9(3):e93156.
Heselpoth RD, Owens JM, Nelson DC. Quantitative analysis of the thermal stability of the gamma phage endolysin PlyG: A biophysical and kinetic approach to assaying therapeutic potential. Virology. 2014 .
2012
Heselpoth RD, Nelson DC. A new screening method for the directed evolution of thermostable bacteriolytic enzymes. J Vis Exp. 2012 ;(69).
McGowan S, Buckle AM, Mitchell MS, Hoopes JT, D Gallagher T, Heselpoth RD, Shen Y, Reboul CF, Law RHP, Fischetti VA, et al. X-ray crystal structure of the streptococcal specific phage lysin PlyC. Proc Natl Acad Sci U S A. 2012 ;109(31):12752-7.