Publications

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Active destabilization of base pairs by a DNA glycosylase wedge initiates damage recognition.
Kuznetsov NA, Bergonzo C, Campbell AJ, Li H, Mechetin GV, de los Santos C, Grollman AP, Fedorova OS, Zharkov DO, Simmerling C. 2015. Active destabilization of base pairs by a DNA glycosylase wedge initiates damage recognition. Nucleic acids research 43(1): 272-81. DOI: 10.1093/nar/gku1300
High accuracy of Karplus equations for relating three-bond J couplings to protein backbone torsion angles.
Li F, Lee JH, Grishaev A, Ying J, Bax A. 2015. High accuracy of Karplus equations for relating three-bond J couplings to protein backbone torsion angles. Chemphyschem : a European journal of chemical physics and physical chemistry 16(3): 572-8. DOI: 10.1002/cphc.201402704
HIV. Expanding the breadth of an HIV-1 vaccine.
Ofek G, Diskin R. 2014. HIV. Expanding the breadth of an HIV-1 vaccine. Science (New York, N.Y.) 346(6215): 1290-1. DOI: 10.1126/science.aaa2315
Resolving self-association of a therapeutic antibody by formulation optimization and molecular approaches.
Casaz P, Boucher E, Wollacott R, Pierce BG, Rivera R, Sedic M, Ozturk S, Thomas WD, Wang Y. 2014. Resolving self-association of a therapeutic antibody by formulation optimization and molecular approaches. mAbs 6(6): 1533-9. DOI: 10.4161/19420862.2014.975658
Modulation of RNA polymerase II phosphorylation downstream of pathogen perception orchestrates plant immunity.
Li F, Cheng C, Cui F, de Oliveira MV, Yu X, Meng X, Intorne AC, Babilonia K, Li M, Li B, et al. 2014. Modulation of RNA polymerase II phosphorylation downstream of pathogen perception orchestrates plant immunity. Cell host & microbe 16(6): 748-58. DOI: 10.1016/j.chom.2014.10.018
Small molecule inhibitors of Ago2 decrease Venezuelan equine encephalitis virus replication.
Madsen C, Hooper I, Lundberg L, Shafagati N, Johnson A, Senina S, de la Fuente C, Hoover LI, Fredricksen BL, Dinman J, et al. 2014. Small molecule inhibitors of Ago2 decrease Venezuelan equine encephalitis virus replication. Antiviral research 112: 26-37. DOI: 10.1016/j.antiviral.2014.10.002
Structural interactions of a voltage sensor toxin with lipid membranes.
Mihailescu M, Krepkiy D, Milescu M, Gawrisch K, Swartz KJ, White S. 2014. Structural interactions of a voltage sensor toxin with lipid membranes. Proceedings of the National Academy of Sciences of the United States of America 111(50): E5463-70. DOI: 10.1073/pnas.1415324111
Quantitative analysis of the thermal stability of the gamma phage endolysin PlyG: a biophysical and kinetic approach to assaying therapeutic potential.
Heselpoth RD, Owens JM, Nelson DC. 2015. Quantitative analysis of the thermal stability of the gamma phage endolysin PlyG: a biophysical and kinetic approach to assaying therapeutic potential. Virology 477: 125-132. DOI: 10.1016/j.virol.2014.11.003
Trajectories of the ribosome as a Brownian nanomachine.
Dashti A, Schwander P, Langlois R, Fung R, Li W, Hosseinizadeh A, Liao HY, Pallesen J, Sharma G, Stupina VA, et al. 2014. Trajectories of the ribosome as a Brownian nanomachine. Proceedings of the National Academy of Sciences of the United States of America 111(49): 17492-7. DOI: 10.1073/pnas.1419276111
Archaeal DNA replication.
Kelman LM, Kelman Z. 2014. Archaeal DNA replication. Annual review of genetics 48: 71-97. DOI: 10.1146/annurev-genet-120213-092148
Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Bird GH, Irimia A, Ofek G, Kwong PD, Wilson IA, Walensky LD. 2014. Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies. Nature structural & molecular biology 21(12): 1058-67. DOI: 10.1038/nsmb.2922
Characterization of AlgMsp, an alginate lyase from Microbulbifer sp. 6532A.
Swift SM, Hudgens JW, Heselpoth RD, Bales PM, Nelson DC. 2014. Characterization of AlgMsp, an alginate lyase from Microbulbifer sp. 6532A. PloS one 9(11): e112939. DOI: 10.1371/journal.pone.0112939
Molecular biology: Entry signals control development.
Dinman JD. 2015. Molecular biology: Entry signals control development. Nature 517(7532): 24-5. DOI: 10.1038/nature14069
Detection of contaminating enzymatic activity in plant-derived recombinant biotechnology products.
Brinson RG, Giulian GG, Kelman Z, Marino JP. 2014. Detection of contaminating enzymatic activity in plant-derived recombinant biotechnology products. Analytical chemistry 86(23): 11508-12. DOI: 10.1021/ac503864m
Isolated perioperative hypertension: clinical implications & contemporary treatment strategies.
Dodson GM, Bentley WE, Awad A, Muntazar M, Goldberg ME. 2014. Isolated perioperative hypertension: clinical implications & contemporary treatment strategies. Current hypertension reviews 10(1): 31-6.