Publications

Galeterone and VNPT55 disrupt Mnk-eIF4E to inhibit prostate cancer cell migration and invasion.
Kwegyir-Afful AK, Bruno RD, Purushottamachar P, Murigi FN, Njar VC. 2016. Galeterone and VNPT55 disrupt Mnk-eIF4E to inhibit prostate cancer cell migration and invasion. The FEBS journal 283(21): 3898-3918. DOI: 10.1111/febs.13895
How Carrier Size and Valency Modulate Receptor-Mediated Signaling: Understanding the Link between Binding and Endocytosis of ICAM-1-Targeted Carriers.
Serrano D, Manthe RL, Paul E, Chadha R, Muro S. 2016. How Carrier Size and Valency Modulate Receptor-Mediated Signaling: Understanding the Link between Binding and Endocytosis of ICAM-1-Targeted Carriers. Biomacromolecules 17(10): 3127-3137.
Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Coey CT, Malik SS, Pidugu LS, Varney KM, Pozharski E, Drohat AC. 2016. Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic acids research 44(21): 10248-10258.
Probing the Action of Chemical Denaturant on an Intrinsically Disordered Protein by Simulation and Experiment.
Zheng W, Borgia A, Buholzer K, Grishaev A, Schuler B, Best RB. 2016. Probing the Action of Chemical Denaturant on an Intrinsically Disordered Protein by Simulation and Experiment. Journal of the American Chemical Society 138(36): 11702-13. DOI: 10.1021/jacs.6b05443
Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods.
Borgia A, Zheng W, Buholzer K, Borgia MB, Schüler A, Hofmann H, Soranno A, Nettels D, Gast K, Grishaev A, et al. 2016. Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods. Journal of the American Chemical Society 138(36): 11714-26. DOI: 10.1021/jacs.6b05917
Structure of the STRA6 receptor for retinol uptake.
Chen Y, Clarke OB, Kim J, Stowe S, Kim YK, Assur Z, Cavalier M, Godoy-Ruiz R, von Alpen DC, Manzini C, et al. 2016. Structure of the STRA6 receptor for retinol uptake. Science (New York, N.Y.) 353(6302): . DOI: 10.1126/science.aad8266
Constructing "quantized quorums" to guide emergent phenotypes through quorum quenching capsules.
Zargar A, Quan DN, Abutaleb N, Choi E, Terrell JL, Payne GF, Bentley WE. 2017. Constructing "quantized quorums" to guide emergent phenotypes through quorum quenching capsules. Biotechnology and bioengineering 114(2): 407-415. DOI: 10.1002/bit.26080
Data on biochemical fluxes generated from biofabricated enzyme complexes assembled through engineered tags and microbial transglutaminase.
Bhokisham N, Pakhchanian H, Quan D, Tschirhart T, Tsao CY, Payne GF, Bentley WE. 2016. Data on biochemical fluxes generated from biofabricated enzyme complexes assembled through engineered tags and microbial transglutaminase. Data in brief 8: 1031-5. DOI: 10.1016/j.dib.2016.07.005
Estimating glycosaminoglycan-protein interaction affinity: water dominates the specific antithrombin-heparin interaction.
Sarkar A, Yu W, Desai UR, MacKerell AD, Mosier PD. 2016. Estimating glycosaminoglycan-protein interaction affinity: water dominates the specific antithrombin-heparin interaction. Glycobiology 26(10): 1041-1047. DOI: 10.1093/glycob/cww073
Multiple Evolutionary Events Involved in Maintaining Homologs of Resistance to Powdery Mildew 8 in Brassica napus.
Li Q, Li J, Sun JL, Ma XF, Wang TT, Berkey R, Yang H, Niu YZ, Fan J, Li Y, et al. 2016. Multiple Evolutionary Events Involved in Maintaining Homologs of Resistance to Powdery Mildew 8 in Brassica napus. Frontiers in plant science 7: 1065. DOI: 10.3389/fpls.2016.01065
Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.
Long Y, Xu M, Li R, Dai S, Beers J, Chen G, Soheilian F, Baxa U, Wang M, Marugan JJ, et al. 2016. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A. Stem cells translational medicine 5(12): 1644-1655.
Dissecting major signaling pathways in prostate cancer development and progression: Mechanisms and novel therapeutic targets.
Ramalingam S, Ramamurthy VP, Njar VCO. 2017. Dissecting major signaling pathways in prostate cancer development and progression: Mechanisms and novel therapeutic targets. The Journal of steroid biochemistry and molecular biology 166: 16-27. DOI: 10.1016/j.jsbmb.2016.07.006
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.
Cardenas MG, Yu W, Beguelin W, Teater MR, Geng H, Goldstein RL, Oswald E, Hatzi K, Yang SN, Cohen J, et al. 2016. Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma. The Journal of clinical investigation 126(9): 3351-62. DOI: 10.1172/JCI85795
Conferring biological activity to native spider silk: A biofunctionalized protein-based microfiber.
Wu HC, Quan DN, Tsao CY, Liu Y, Terrell JL, Luo X, Yang JC, Payne GF, Bentley WE. 2017. Conferring biological activity to native spider silk: A biofunctionalized protein-based microfiber. Biotechnology and bioengineering 114(1): 83-95. DOI: 10.1002/bit.26065
Intra- and trans-cellular delivery of enzymes by direct conjugation with non-multivalent anti-ICAM molecules.
Ghaffarian R, Roki N, Abouzeid A, Vreeland W, Muro S. 2016. Intra- and trans-cellular delivery of enzymes by direct conjugation with non-multivalent anti-ICAM molecules. Journal of controlled release : official journal of the Controlled Release Society 238: 221-230. DOI: 10.1016/j.jconrel.2016.07.042