Publications

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Combined use of residual dipolar couplings and solution X-ray scattering to rapidly probe rigid-body conformational transitions in a non-phosphorylatable active-site mutant of the 128 kDa enzyme I dimer.
Takayama Y, Schwieters CD, Grishaev A, Ghirlando R, Clore GM. 2011. Combined use of residual dipolar couplings and solution X-ray scattering to rapidly probe rigid-body conformational transitions in a non-phosphorylatable active-site mutant of the 128 kDa enzyme I dimer. Journal of the American Chemical Society 133(3): 424-7. DOI: 10.1021/ja109866w
Different residues on the surface of the Methanothermobacter thermautotrophicus MCM helicase interact with single- and double-stranded DNA.
Sakakibara N, Kasiviswanathan R, Kelman Z. 2010. Different residues on the surface of the Methanothermobacter thermautotrophicus MCM helicase interact with single- and double-stranded DNA. Archaea (Vancouver, B.C.) 2010: 505693. DOI: 10.1155/2010/505693
Toxicogenomic response of Mycobacterium bovis BCG to peracetic acid and a comparative analysis of the M. bovis BCG response to three oxidative disinfectants.
Nde CW, Toghrol F, Jang HJ, Bentley WE. 2011. Toxicogenomic response of Mycobacterium bovis BCG to peracetic acid and a comparative analysis of the M. bovis BCG response to three oxidative disinfectants. Applied microbiology and biotechnology 90(1): 277-304. DOI: 10.1007/s00253-010-2931-6
In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.
Wilder PT, Charpentier TH, Liriano MA, Gianni K, Varney KM, Pozharski E, Coop A, Toth EA, Mackerell AD, Weber DJ. 2010. In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction. International journal of high throughput screening 2010(1): 109-126.
CYP17 inhibitors for prostate cancer therapy.
Vasaitis TS, Bruno RD, Njar VC. 2011. CYP17 inhibitors for prostate cancer therapy. The Journal of steroid biochemistry and molecular biology 125(1-2): 23-31. DOI: 10.1016/j.jsbmb.2010.11.005
Active-site structure of class IV adenylyl cyclase and transphyletic mechanism.
Gallagher DT, Kim SK, Robinson H, Reddy PT. 2011. Active-site structure of class IV adenylyl cyclase and transphyletic mechanism. Journal of molecular biology 405(3): 787-803. DOI: 10.1016/j.jmb.2010.11.026
High-throughput Giardia lamblia viability assay using bioluminescent ATP content measurements.
Chen CZ, Kulakova L, Southall N, Marugan JJ, Galkin A, Austin CP, Herzberg O, Zheng W. 2011. High-throughput Giardia lamblia viability assay using bioluminescent ATP content measurements. Antimicrobial agents and chemotherapy 55(2): 667-75. DOI: 10.1128/AAC.00618-10
Formation of salt bridges mediates internal dimerization of myosin VI medial tail domain.
Kim H, Hsin J, Liu Y, Selvin PR, Schulten K. 2010. Formation of salt bridges mediates internal dimerization of myosin VI medial tail domain. Structure (London, England : 1993) 18(11): 1443-9. DOI: 10.1016/j.str.2010.09.011
Kinetic studies of drug-protein interactions by using peak profiling and high-performance affinity chromatography: examination of multi-site interactions of drugs with human serum albumin columns.
Tong Z, Schiel JE, Papastavros E, Ohnmacht CM, Smith QR, Hage DS. 2011. Kinetic studies of drug-protein interactions by using peak profiling and high-performance affinity chromatography: examination of multi-site interactions of drugs with human serum albumin columns. Journal of chromatography. A 1218(15): 2065-71. DOI: 10.1016/j.chroma.2010.10.070
Unique properties of the Mtr4p-poly(A) complex suggest a role in substrate targeting.
Bernstein J, Ballin JD, Patterson DN, Wilson GM, Toth EA. 2010. Unique properties of the Mtr4p-poly(A) complex suggest a role in substrate targeting. Biochemistry 49(49): 10357-70. DOI: 10.1021/bi101518x
Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
Fernández MM, Cho S, De Marzi MC, Kerzic MC, Robinson H, Mariuzza RA, Malchiodi EL. 2011. Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain. The Journal of biological chemistry 286(2): 1189-95. DOI: 10.1074/jbc.M110.142471
Quantification of cholesterol-metabolizing P450s CYP27A1 and CYP46A1 in neural tissues reveals a lack of enzyme-product correlations in human retina but not human brain.
Liao WL, Heo GY, Dodder NG, Reem RE, Mast N, Huang S, Dipatre PL, Turko IV, Pikuleva IA. 2011. Quantification of cholesterol-metabolizing P450s CYP27A1 and CYP46A1 in neural tissues reveals a lack of enzyme-product correlations in human retina but not human brain. Journal of proteome research 10(1): 241-8. DOI: 10.1021/pr1008898
Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease.
Hsu J, Serrano D, Bhowmick T, Kumar K, Shen Y, Kuo YC, Garnacho C, Muro S. 2011. Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease. Journal of controlled release : official journal of the Controlled Release Society 149(3): 323-31. DOI: 10.1016/j.jconrel.2010.10.031
Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers.
Calderon AJ, Bhowmick T, Leferovich J, Burman B, Pichette B, Muzykantov V, Eckmann DM, Muro S. 2011. Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers. Journal of controlled release : official journal of the Controlled Release Society 150(1): 37-44. DOI: 10.1016/j.jconrel.2010.10.025
Mechanism of inactivation of Escherichia coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid .
Liu D, Pozharski E, Fu M, Silverman RB, Ringe D. 2010. Mechanism of inactivation of Escherichia coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid . Biochemistry 49(49): 10507-15. DOI: 10.1021/bi101325z