Publications

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RESISTANCE TO POWDERY MILDEW8.1 boosts pattern-triggered immunity against multiple pathogens in Arabidopsis and rice.
Li Y, Zhang Y, Wang QX, Wang TT, Cao XL, Zhao ZX, Zhao SL, Xu YJ, Xiao ZY, Li JL, et al. 2018. RESISTANCE TO POWDERY MILDEW8.1 boosts pattern-triggered immunity against multiple pathogens in Arabidopsis and rice. Plant biotechnology journal 16(2): 428-441. DOI: 10.1111/pbi.12782
In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds.
Mast N, Anderson KW, Johnson KM, Phan TTN, Guengerich FP, Pikuleva IA. 2017. In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds. The Journal of biological chemistry 292(31): 12934-12946. DOI: 10.1074/jbc.M117.794909
Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.
Daneshjou R, Wang Y, Bromberg Y, Bovo S, Martelli PL, Babbi G, Lena PD, Casadio R, Edwards M, Gifford D, et al. 2017. Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges. Human mutation 38(9): 1182-1192. DOI: 10.1002/humu.23280
Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice.
Garnacho C, Dhami R, Solomon M, Schuchman EH, Muro S. 2017. Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice. Molecular therapy : the journal of the American Society of Gene Therapy 25(7): 1686-1696. DOI: 10.1016/j.ymthe.2017.05.014
A protein-protein interaction dictates Borrelial infectivity.
Thakur M, Sharma K, Chao K, Smith AA, Herzberg O, Pal U. 2017. A protein-protein interaction dictates Borrelial infectivity. Scientific reports 7(1): 2932. DOI: 10.1038/s41598-017-03279-7
Validation of Protein-Ligand Crystal Structure Models: Small Molecule and Peptide Ligands.
Pozharski E, Deller MC, Rupp B. 2017. Validation of Protein-Ligand Crystal Structure Models: Small Molecule and Peptide Ligands. Methods in molecular biology (Clifton, N.J.) 1607: 611-625. DOI: 10.1007/978-1-4939-7000-1_25
PCPP-Adjuvanted Respiratory Syncytial Virus (RSV) sF Subunit Vaccine: Self-Assembled Supramolecular Complexes Enable Enhanced Immunogenicity and Protection.
Cayatte C, Marin A, Rajani GM, Schneider-Ohrum K, Snell Bennett A, Marshall JD, Andrianov AK. 2017. PCPP-Adjuvanted Respiratory Syncytial Virus (RSV) sF Subunit Vaccine: Self-Assembled Supramolecular Complexes Enable Enhanced Immunogenicity and Protection. Molecular pharmaceutics 14(7): 2285-2293. DOI: 10.1021/acs.molpharmaceut.7b00118
Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges.
Cai B, Li B, Kiga N, Thusberg J, Bergquist T, Chen YC, Niknafs N, Carter H, Tokheim C, Beleva-Guthrie V, et al. 2017. Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges. Human mutation 38(9): 1266-1276. DOI: 10.1002/humu.23265
Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges.
Yin Y, Kundu K, Pal LR, Moult J. 2017. Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges. Human mutation 38(9): 1109-1122. DOI: 10.1002/humu.23267
Biodegradable "Smart" Polyphosphazenes with Intrinsic Multifunctionality as Intracellular Protein Delivery Vehicles.
Martinez AP, Qamar B, Fuerst TR, Muro S, Andrianov AK. 2017. Biodegradable "Smart" Polyphosphazenes with Intrinsic Multifunctionality as Intracellular Protein Delivery Vehicles. Biomacromolecules 18(6): 2000-2011. DOI: 10.1021/acs.biomac.7b00537
Biofabrication of Tobacco mosaic virus-nanoscaffolded supercapacitors via temporal capillary microfluidics.
Zang F, Chu S, Gerasopoulos K, Culver JN, Ghodssi R. 2017. Biofabrication of Tobacco mosaic virus-nanoscaffolded supercapacitors via temporal capillary microfluidics. Nanotechnology 28(26): 265301. DOI: 10.1088/1361-6528/aa742f
Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.
Zhao X, Howell KA, He S, Brannan JM, Wec AZ, Davidson E, Turner HL, Chiang CI, Lei L, Fels JM, et al. 2017. Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell 169(5): 891-904.e15. DOI: 10.1016/j.cell.2017.04.038
CAGI4 Crohn's exome challenge: Marker SNP versus exome variant models for assigning risk of Crohn disease.
Pal LR, Kundu K, Yin Y, Moult J. 2017. CAGI4 Crohn's exome challenge: Marker SNP versus exome variant models for assigning risk of Crohn disease. Human mutation 38(9): 1225-1234. DOI: 10.1002/humu.23256
CAGI4 SickKids clinical genomes challenge: A pipeline for identifying pathogenic variants.
Pal LR, Kundu K, Yin Y, Moult J. 2017. CAGI4 SickKids clinical genomes challenge: A pipeline for identifying pathogenic variants. Human mutation 38(9): 1169-1181. DOI: 10.1002/humu.23257
Lysosomal enzyme replacement therapies: Historical development, clinical outcomes, and future perspectives.
Solomon M, Muro S. 2017. Lysosomal enzyme replacement therapies: Historical development, clinical outcomes, and future perspectives. Advanced drug delivery reviews 118: 109-134. DOI: 10.1016/j.addr.2017.05.004