Publications

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Facile Synthesis of Spirocyclic Lactams from β-Keto Carboxylic Acids.
Yang W, Sun X, Yu W, Rai R, Deschamps JR, Mitchell LA, Jiang C, MacKerell AD, Xue F. 2015. Facile Synthesis of Spirocyclic Lactams from β-Keto Carboxylic Acids. Organic letters 17(12): 3070-3. DOI: 10.1021/acs.orglett.5b01350
Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.
Liao Z, Gu L, Vergalli J, Mariani SA, De Dominici M, Lokareddy RK, Dagvadorj A, Purushottamachar P, McCue PA, Trabulsi E, et al. 2015. Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia. Molecular cancer therapeutics 14(8): 1777-93. DOI: 10.1158/1535-7163.MCT-14-0883
A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation.
Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, et al. 2015. A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation. PloS one 10(5): e0126420. DOI: 10.1371/journal.pone.0126420
Comparing Fast Pressure Jump and Temperature Jump Protein Folding Experiments and Simulations.
Wirth AJ, Liu Y, Prigozhin MB, Schulten K, Gruebele M. 2015. Comparing Fast Pressure Jump and Temperature Jump Protein Folding Experiments and Simulations. Journal of the American Chemical Society 137(22): 7152-7159. DOI: 10.1021/jacs.5b02474
Structure-activity exploration of a small-molecule Lipid II inhibitor.
Fletcher S, Yu W, Huang J, Kwasny SM, Chauhan J, Opperman TJ, MacKerell AD, de Leeuw E. 2015. Structure-activity exploration of a small-molecule Lipid II inhibitor. Drug design, development and therapy 9: 2383-94. DOI: 10.2147/DDDT.S79504
Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1.
Han J, Shuvaev VV, Davies PF, Eckmann DM, Muro S, Muzykantov VR. 2015. Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1. Journal of controlled release : official journal of the Controlled Release Society 210: 39-47. DOI: 10.1016/j.jconrel.2015.05.006
Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization.
Phad GE, Vázquez Bernat N, Feng Y, Ingale J, Martinez Murillo PA, O'Dell S, Li Y, Mascola JR, Sundling C, Wyatt RT, et al. 2015. Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization. Journal of immunology (Baltimore, Md. : 1950) 194(12): 5903-14. DOI: 10.4049/jimmunol.1500122
Quantification of histone deacetylase isoforms in human frontal cortex, human retina, and mouse brain.
Anderson KW, Chen J, Wang M, Mast N, Pikuleva IA, Turko IV. 2015. Quantification of histone deacetylase isoforms in human frontal cortex, human retina, and mouse brain. PloS one 10(5): e0126592. DOI: 10.1371/journal.pone.0126592
Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association Studies.
Pal LR, Moult J. 2015. Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association Studies. Journal of molecular biology 427(13): 2271-89. DOI: 10.1016/j.jmb.2015.04.014
Self-assembly with orthogonal-imposed stimuli to impart structure and confer magnetic function to electrodeposited hydrogels.
Li Y, Liu Y, Gao T, Zhang B, Song Y, Terrell JL, Barber N, Bentley WE, Takeuchi I, Payne GF, et al. 2015. Self-assembly with orthogonal-imposed stimuli to impart structure and confer magnetic function to electrodeposited hydrogels. ACS applied materials & interfaces 7(19): 10587-98. DOI: 10.1021/acsami.5b02339
Rational design of 'controller cells' to manipulate protein and phenotype expression.
Zargar A, Quan DN, Emamian M, Tsao CY, Wu HC, Virgile CR, Bentley WE. 2015. Rational design of 'controller cells' to manipulate protein and phenotype expression. Metabolic engineering 30: 61-68. DOI: 10.1016/j.ymben.2015.04.001
Altered Clathrin-Independent Endocytosis in Type A Niemann-Pick Disease Cells and Rescue by ICAM-1-Targeted Enzyme Delivery.
Rappaport J, Manthe RL, Garnacho C, Muro S. 2015. Altered Clathrin-Independent Endocytosis in Type A Niemann-Pick Disease Cells and Rescue by ICAM-1-Targeted Enzyme Delivery. Molecular pharmaceutics 12(5): 1366-76. DOI: 10.1021/mp5005959
Dominant negative RPW8.2 fusion proteins reveal the importance of haustorium-oriented protein trafficking for resistance against powdery mildew in Arabidopsis.
Zhang Q, Berkey R, Pan Z, Wang W, Zhang Y, Ma X, King H, Xiao S. 2015. Dominant negative RPW8.2 fusion proteins reveal the importance of haustorium-oriented protein trafficking for resistance against powdery mildew in Arabidopsis. Plant signaling & behavior 10(3): e989766. DOI: 10.4161/15592324.2014.989766
The roles of family B and D DNA polymerases in Thermococcus species 9°N Okazaki fragment maturation.
Greenough L, Kelman Z, Gardner AF. 2015. The roles of family B and D DNA polymerases in Thermococcus species 9°N Okazaki fragment maturation. The Journal of biological chemistry 290(20): 12514-22. DOI: 10.1074/jbc.M115.638130
Plant virus directed fabrication of nanoscale materials and devices.
Culver JN, Brown AD, Zang F, Gnerlich M, Gerasopoulos K, Ghodssi R. 2015. Plant virus directed fabrication of nanoscale materials and devices. Virology 479-480: 200-12. DOI: 10.1016/j.virol.2015.03.008