Publications

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Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI.
Carraro M, Minervini G, Giollo M, Bromberg Y, Capriotti E, Casadio R, Dunbrack R, Elefanti L, Fariselli P, Ferrari C, et al. 2017. Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI. Human mutation 38(9): 1042-1050. DOI: 10.1002/humu.23235
Water Proton NMR: A Tool for Protein Aggregation Characterization.
Taraban MB, DePaz RA, Lobo B, Yu YB. 2017. Water Proton NMR: A Tool for Protein Aggregation Characterization. Analytical chemistry 89(10): 5494-5502. DOI: 10.1021/acs.analchem.7b00464
Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8+ TCR Repertoires to Immunodominant Viral Antigens.
Chen G, Yang X, Ko A, Sun X, Gao M, Zhang Y, Shi A, Mariuzza RA, Weng NP. 2017. Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8+ TCR Repertoires to Immunodominant Viral Antigens. Cell reports 19(3): 569-583. DOI: 10.1016/j.celrep.2017.03.072
Structural features and lipid binding domain of tubulin on biomimetic mitochondrial membranes.
Hoogerheide DP, Noskov SY, Jacobs D, Bergdoll L, Silin V, Worcester DL, Abramson J, Nanda H, Rostovtseva TK, Bezrukov SM. 2017. Structural features and lipid binding domain of tubulin on biomimetic mitochondrial membranes. Proceedings of the National Academy of Sciences of the United States of America 114(18): E3622-E3631. DOI: 10.1073/pnas.1619806114
The GAN Exonuclease or the Flap Endonuclease Fen1 and RNase HII Are Necessary for Viability of Thermococcus kodakarensis.
Burkhart BW, Cubonova L, Heider MR, Kelman Z, Reeve JN, Santangelo TJ. 2017. The GAN Exonuclease or the Flap Endonuclease Fen1 and RNase HII Are Necessary for Viability of Thermococcus kodakarensis. Journal of bacteriology 199(13): . DOI: 10.1128/JB.00141-17
Reliable clinical serum analysis with reusable electrochemical sensor: Toward point-of-care measurement of the antipsychotic medication clozapine.
Kang M, Kim E, Winkler TE, Banis G, Liu Y, Kitchen CA, Kelly DL, Ghodssi R, Payne GF. 2017. Reliable clinical serum analysis with reusable electrochemical sensor: Toward point-of-care measurement of the antipsychotic medication clozapine. Biosensors & bioelectronics 95: 55-59. DOI: 10.1016/j.bios.2017.04.008
The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP.
Melville Z, Hernández-Ochoa EO, Pratt SJP, Liu Y, Pierce AD, Wilder PT, Adipietro KA, Breysse DH, Varney KM, Schneider MF, et al. 2017. The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP. Biochemistry 56(17): 2328-2337. DOI: 10.1021/acs.biochem.7b00117
Investigating the ion dependence of the first unfolding step of GTPase-Associating Center ribosomal RNA.
Hayatshahi HS, Bergonzo C, Cheatham TE. 2018. Investigating the ion dependence of the first unfolding step of GTPase-Associating Center ribosomal RNA. Journal of biomolecular structure & dynamics 36(1): 243-253. DOI: 10.1080/07391102.2016.1274272
Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models.
Hwang IY, Koh E, Wong A, March JC, Bentley WE, Lee YS, Chang MW. 2017. Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models. Nature communications 8: 15028. DOI: 10.1038/ncomms15028
Lessons from the CAGI-4 Hopkins clinical panel challenge.
Chandonia JM, Adhikari A, Carraro M, Chhibber A, Cutting GR, Fu Y, Gasparini A, Jones DT, Kramer A, Kundu K, et al. 2017. Lessons from the CAGI-4 Hopkins clinical panel challenge. Human mutation 38(9): 1155-1168. DOI: 10.1002/humu.23225
Development of a glycoconjugate vaccine to prevent invasive Salmonella Typhimurium infections in sub-Saharan Africa.
Baliban SM, Yang M, Ramachandran G, Curtis B, Shridhar S, Laufer RS, Wang JY, Van Druff J, Higginson EE, Hegerle N, et al. 2017. Development of a glycoconjugate vaccine to prevent invasive Salmonella Typhimurium infections in sub-Saharan Africa. PLoS neglected tropical diseases 11(4): e0005493. DOI: 10.1371/journal.pntd.0005493
Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.
Pidugu LS, Neu H, Wong TL, Pozharski E, Molloy JL, Michel SL, Toth EA. 2017. Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site. Acta crystallographica. Section D, Structural biology 73(Pt 4): 340-348. DOI: 10.1107/S2059798317002029
X-ray crystal structure of human calcium-bound S100A1.
Melville Z, Aligholizadeh E, McKnight LE, Weber DJ, Pozharski E, Weber DJ. 2017. X-ray crystal structure of human calcium-bound S100A1. Acta crystallographica. Section F, Structural biology communications 73(Pt 4): 215-221. DOI: 10.1107/S2053230X17003983
Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif.
Coburn K, Melville Z, Aligholizadeh E, Roth BM, Varney KM, Carrier F, Pozharski E, Weber DJ. 2017. Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Acta crystallographica. Section F, Structural biology communications 73(Pt 4): 209-214. DOI: 10.1107/S2053230X17003454
Microfluidic Arrayed Lab-On-A-Chip for Electrochemical Capacitive Detection of DNA Hybridization Events.
Ben-Yoav H, Dykstra PH, Bentley WE, Ghodssi R. 2017. Microfluidic Arrayed Lab-On-A-Chip for Electrochemical Capacitive Detection of DNA Hybridization Events. Methods in molecular biology (Clifton, N.J.) 1572: 71-88. DOI: 10.1007/978-1-4939-6911-1_6