Publications

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Cutting edge: Evidence for a dynamically driven T cell signaling mechanism.
Hawse WF, Champion MM, Joyce MV, Hellman LM, Hossain M, Ryan V, Pierce BG, Weng Z, Baker BM. 2012. Cutting edge: Evidence for a dynamically driven T cell signaling mechanism. Journal of immunology (Baltimore, Md. : 1950) 188(12): 5819-23. DOI: 10.4049/jimmunol.1200952
Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1.
Godbole AM, Purushottamachar P, Martin MS, Njar VC. 2012. Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1. Cancer chemotherapy and pharmacology 70(2): 339-44. DOI: 10.1007/s00280-012-1877-z
Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
Maiti A, Noon MS, MacKerell AD, Pozharski E, Drohat AC. 2012. Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA. Proceedings of the National Academy of Sciences of the United States of America 109(21): 8091-6. DOI: 10.1073/pnas.1201010109
Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.
Manvilla BA, Maiti A, Begley MC, Toth EA, Drohat AC. 2012. Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA. Journal of molecular biology 420(3): 164-75. DOI: 10.1016/j.jmb.2012.04.028
Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124.
Simone EA, Zern BJ, Chacko AM, Mikitsh JL, Blankemeyer ER, Muro S, Stan RV, Muzykantov VR. 2012. Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124. Biomaterials 33(21): 5406-13. DOI: 10.1016/j.biomaterials.2012.04.036
Exploring the DNA-recognition potential of homeodomains.
Chu SW, Noyes MB, Christensen RG, Pierce BG, Zhu LJ, Weng Z, Stormo GD, Wolfe SA. 2012. Exploring the DNA-recognition potential of homeodomains. Genome research 22(10): 1889-98. DOI: 10.1101/gr.139014.112
Effect of thiol pendant conjugates on plasmid DNA binding, release, and stability of polymeric delivery vectors.
Bacalocostantis I, Mane VP, Kang MS, Goodley AS, Muro S, Kofinas P. 2012. Effect of thiol pendant conjugates on plasmid DNA binding, release, and stability of polymeric delivery vectors. Biomacromolecules 13(5): 1331-9. DOI: 10.1021/bm3004786
Biofabrication of stratified biofilm mimics for observation and control of bacterial signaling.
Luo X, Wu HC, Tsao CY, Cheng Y, Betz J, Payne GF, Rubloff GW, Bentley WE. 2012. Biofabrication of stratified biofilm mimics for observation and control of bacterial signaling. Biomaterials 33(20): 5136-43. DOI: 10.1016/j.biomaterials.2012.03.037
DNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion.
Suhasini AN, Sommers JA, Yu S, Wu Y, Xu T, Kelman Z, Kaplan DL, Brosh RM. 2012. DNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion. The Journal of biological chemistry 287(23): 19188-98. DOI: 10.1074/jbc.M112.352757
Imino hydrogen positions in nucleic acids from density functional theory validated by NMR residual dipolar couplings.
Grishaev A, Ying J, Bax A. 2012. Imino hydrogen positions in nucleic acids from density functional theory validated by NMR residual dipolar couplings. Journal of the American Chemical Society 134(16): 6956-9. DOI: 10.1021/ja301775j
Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect.
West AL, Evans SE, González JM, Carter LG, Tsuruta H, Pozharski E, Michel SL. 2012. Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect. Proceedings of the National Academy of Sciences of the United States of America 109(15): 5633-8. DOI: 10.1073/pnas.1120283109
Interrogation of MDM2 phosphorylation in p53 activation using native chemical ligation: the functional role of Ser17 phosphorylation in MDM2 reexamined.
Zhan C, Varney K, Yuan W, Zhao L, Lu W. 2012. Interrogation of MDM2 phosphorylation in p53 activation using native chemical ligation: the functional role of Ser17 phosphorylation in MDM2 reexamined. Journal of the American Chemical Society 134(15): 6855-64. DOI: 10.1021/ja301255n
On the need for an international effort to capture, share and use crystallization screening data.
Newman J, Bolton EE, Müller-Dieckmann J, Fazio VJ, Gallagher DT, Lovell D, Luft JR, Peat TS, Ratcliffe D, Sayle RA, et al. 2012. On the need for an international effort to capture, share and use crystallization screening data. Acta crystallographica. Section F, Structural biology and crystallization communications 68(Pt 3): 253-8. DOI: 10.1107/S1744309112002618
Altering the communication networks of multispecies microbial systems using a diverse toolbox of AI-2 analogues.
Gamby S, Roy V, Guo M, Smith JA, Wang J, Stewart JE, Wang X, Bentley WE, Sintim HO. 2012. Altering the communication networks of multispecies microbial systems using a diverse toolbox of AI-2 analogues. ACS chemical biology 7(6): 1023-30. DOI: 10.1021/cb200524y
Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4.
Yin Y, Wang XX, Mariuzza RA. 2012. Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proceedings of the National Academy of Sciences of the United States of America 109(14): 5405-10. DOI: 10.1073/pnas.1118801109