Publications

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Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme.
Yuzhakov A, Kelman Z, Hurwitz J, O'Donnell M. 1999. Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme. The EMBO journal 18(21): 6189-99.
Some measures of comparative performance in the three CASPs.
Venclovas C, Zemla A, Fidelis K, Moult J. 1999. Some measures of comparative performance in the three CASPs. Proteins Suppl 3: 231-7.
Processing and analysis of CASP3 protein structure predictions.
Zemla A, Venclovas C, Moult J, Fidelis K. 1999. Processing and analysis of CASP3 protein structure predictions. Proteins Suppl 3: 22-9.
Critical assessment of methods of protein structure prediction (CASP): round III.
Moult J, Hubbard T, Fidelis K, Pedersen JT. 1999. Critical assessment of methods of protein structure prediction (CASP): round III. Proteins Suppl 3: 2-6.
Studies of the molecular mechanism of discrimination between cGMP and cAMP in the allosteric sites of the cGMP-binding cGMP-specific phosphodiesterase (PDE5).
Turko IV, Francis SH, Corbin JD. 1999. Studies of the molecular mechanism of discrimination between cGMP and cAMP in the allosteric sites of the cGMP-binding cGMP-specific phosphodiesterase (PDE5). The Journal of biological chemistry 274(41): 29038-41.
Local electrostatic optimization in proteins.
Oliva MT, Moult J. 1999. Local electrostatic optimization in proteins. Protein engineering 12(9): 727-35.
Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH.
Kelman Z, Pietrokovski S, Hurwitz J. 1999. Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH. The Journal of biological chemistry 274(40): 28751-61.
The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity.
Kelman Z, Zuo S, Arroyo MP, Wang TS, Hurwitz J. 1999. The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity. Proceedings of the National Academy of Sciences of the United States of America 96(17): 9515-20.
On the possibility of constructive neutral evolution.
Stoltzfus A. 1999. On the possibility of constructive neutral evolution. Journal of molecular evolution 49(2): 169-81.
Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
Chen CC, Herzberg O. 1999. Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp. Protein engineering 12(7): 573-9.
Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds.
Turko IV, Ballard SA, Francis SH, Corbin JD. 1999. Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds. Molecular pharmacology 56(1): 124-30.
Helix swapping between two alpha/beta barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg(2+)-oxalate.
Huang K, Li Z, Jia Y, Dunaway-Mariano D, Herzberg O. 1999. Helix swapping between two alpha/beta barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg(2+)-oxalate. Structure (London, England : 1993) 7(5): 539-48.
The structural basis of T cell activation by superantigens.
Li H, Llera A, Malchiodi EL, Mariuzza RA. 1999. The structural basis of T cell activation by superantigens. Annual review of immunology 17: 435-66.
Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes.
Andersen PS, Lavoie PM, Sékaly RP, Churchill H, Kranz DM, Schlievert PM, Karjalainen K, Mariuzza RA. 1999. Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes. Immunity 10(4): 473-83.
Protein backbone angle restraints from searching a database for chemical shift and sequence homology.
Cornilescu G, Delaglio F, Bax A. 1999. Protein backbone angle restraints from searching a database for chemical shift and sequence homology. Journal of biomolecular NMR 13(3): 289-302.