Publications

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Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif.
Coburn K, Melville Z, Aligholizadeh E, Roth BM, Varney KM, Carrier F, Pozharski E, Weber DJ. 2017. Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Acta crystallographica. Section F, Structural biology communications 73(Pt 4): 209-214. DOI: 10.1107/S2053230X17003454
Microfluidic Arrayed Lab-On-A-Chip for Electrochemical Capacitive Detection of DNA Hybridization Events.
Ben-Yoav H, Dykstra PH, Bentley WE, Ghodssi R. 2017. Microfluidic Arrayed Lab-On-A-Chip for Electrochemical Capacitive Detection of DNA Hybridization Events. Methods in molecular biology (Clifton, N.J.) 1572: 71-88. DOI: 10.1007/978-1-4939-6911-1_6
Twilight reloaded: the peptide experience.
Weichenberger CX, Pozharski E, Rupp B. 2017. Twilight reloaded: the peptide experience. Acta crystallographica. Section D, Structural biology 73(Pt 3): 211-222. DOI: 10.1107/S205979831601620X
Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity.
Kulkarni P, Jolly MK, Jia D, Mooney SM, Bhargava A, Kagohara LT, Chen Y, Hao P, He Y, Veltri RW, et al. 2017. Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity. Proceedings of the National Academy of Sciences of the United States of America 114(13): E2644-E2653. DOI: 10.1073/pnas.1700082114
Two-Way Chemical Communication between Artificial and Natural Cells.
Lentini R, Martín NY, Forlin M, Belmonte L, Fontana J, Cornella M, Martini L, Tamburini S, Bentley WE, Jousson O, et al. 2017. Two-Way Chemical Communication between Artificial and Natural Cells. ACS central science 3(2): 117-123. DOI: 10.1021/acscentsci.6b00330
Targeting of protein translation as a new treatment paradigm for prostate cancer.
Ramamurthy VP, Ramalingam S, Kwegyir-Afful AK, Hussain A, Njar VCO. 2017. Targeting of protein translation as a new treatment paradigm for prostate cancer. Current opinion in oncology 29(3): 210-220. DOI: 10.1097/CCO.0000000000000367
The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis.
Quigley J, Hughitt VK, Velikovsky CA, Mariuzza RA, El-Sayed NM, Briken V. 2017. The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of <i>Mycobacterium tuberculosis</i>. mBio 8(2): . DOI: 10.1128/mBio.00148-17
Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation.
Liang D, Yu W, Nguyen N, Deschamps JR, Imler GH, Li Y, MacKerell AD, Jiang C, Xue F. 2017. Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation. The Journal of organic chemistry 82(7): 3589-3596. DOI: 10.1021/acs.joc.7b00106
Capillary Microfluidics-Assembled Virus-like Particle Bionanoreceptor Interfaces for Label-Free Biosensing.
Zang F, Gerasopoulos K, Brown AD, Culver JN, Ghodssi R. 2017. Capillary Microfluidics-Assembled Virus-like Particle Bionanoreceptor Interfaces for Label-Free Biosensing. ACS applied materials & interfaces 9(10): 8471-8479. DOI: 10.1021/acsami.6b14045
Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum.
Mast N, Anderson KW, Lin JB, Li Y, Turko IV, Tatsuoka C, Bjorkhem I, Pikuleva IA. 2017. Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum. The Journal of biological chemistry 292(12): 4913-4924. DOI: 10.1074/jbc.M116.774760
A new approach to quantification of mAb aggregates using peptide affinity probes.
Cheung CS, Anderson KW, Patel PM, Cade KL, Phinney KW, Turko IV. 2017. A new approach to quantification of mAb aggregates using peptide affinity probes. Scientific reports 7: 42497. DOI: 10.1038/srep42497
Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein.
Chao KL, Kulakova L, Herzberg O. 2017. Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein. Proceedings of the National Academy of Sciences of the United States of America 114(7): E1128-E1137. DOI: 10.1073/pnas.1616783114
ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes.
Borrman T, Cimons J, Cosiano M, Purcaro M, Pierce BG, Baker BM, Weng Z. 2017. ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes. Proteins 85(5): 908-916. DOI: 10.1002/prot.25260
TumbleScore: Run and tumble analysis for low frame-rate motility videos.
Pottash AE, McKay R, Virgile CR, Ueda H, Bentley WE. 2017. TumbleScore: Run and tumble analysis for low frame-rate motility videos. BioTechniques 62(1): 31-36. DOI: 10.2144/000114493
DNA Deformation-Coupled Recognition of 8-Oxoguanine: Conformational Kinetic Gating in Human DNA Glycosylase.
Li H, Endutkin AV, Bergonzo C, Fu L, Grollman A, Zharkov DO, Simmerling C. 2017. DNA Deformation-Coupled Recognition of 8-Oxoguanine: Conformational Kinetic Gating in Human DNA Glycosylase. Journal of the American Chemical Society 139(7): 2682-2692. DOI: 10.1021/jacs.6b11433