A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS.
| Title | A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS. |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Powers, MA, Koev, ST, Schleunitz, A, Yi, H, Hodzic, V, Bentley, WE, Payne, GF, Rubloff, GW, Ghodssi, R |
| Journal | Lab Chip |
| Volume | 5 |
| Issue | 6 |
| Pagination | 583-6 |
| Date Published | 2005 Jun |
| ISSN | 1473-0197 |
| Keywords | Biomimetics, Biosensing Techniques, Equipment Design, Microfluidics, Microscopy, Fluorescence, Optics and Photonics, Sensitivity and Specificity |
| Abstract | We report a new approach for microfluidic optical bioanalysis that is based on the electrically driven assembly of bio-components on a transparent sidewall and the optical detection of the assembled components using planar waveguides. This allows localized electrical signals for bio-assembly and optical signals for bio-detection that can easily be applied in MEMS systems. We demonstrate a BioMEMS design incorporating this scheme and its output signal when using fluorescent detection. |
| DOI | 10.1039/b503112e |
| Alternate Journal | Lab Chip |
| PubMed ID | 15915249 |