Diffusion of small molecules inside a peptide hydrogel.

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TitleDiffusion of small molecules inside a peptide hydrogel.
Publication TypeJournal Article
Year of Publication2011
AuthorsFeng, Y, Lee, M, Taraban, M, Y Yu, B
JournalChem Commun (Camb)
Volume47
Issue37
Pagination10455-7
Date Published2011 Oct 07
ISSN1364-548X
KeywordsAmino Acid Sequence, Diffusion, Hydrogels, Hydrophobic and Hydrophilic Interactions, Oligopeptides, Phenylalanine
Abstract

A set of four phenylalanine analogues experiences diffusion retardation when transferred from phosphate-buffered saline into a peptide hydrogel of the same pH and ionic strength. The extent of retardation increases linearly with logP(oct), their lipophilicity.

DOI10.1039/c1cc13943f
Alternate JournalChem. Commun. (Camb.)
PubMed ID21853179
PubMed Central IDPMC3271706
Grant ListR01 EB004416 / EB / NIBIB NIH HHS / United States
R01 EB004416-06S1 / EB / NIBIB NIH HHS / United States
R01 EB004416-07 / EB / NIBIB NIH HHS / United States
EB004416 / EB / NIBIB NIH HHS / United States