Using a Redox Modality to Connect Synthetic Biology to Electronics: Hydrogel-Based Chemo-Electro Signal Transduction for Molecular Communication.

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TitleUsing a Redox Modality to Connect Synthetic Biology to Electronics: Hydrogel-Based Chemo-Electro Signal Transduction for Molecular Communication.
Publication TypeJournal Article
Year of Publication2016
AuthorsLiu, Y, Tsao, C-Y, Kim, E, Tschirhart, T, Terrell, JL, Bentley, WE, Payne, GF
JournalAdv Healthc Mater
Date Published2016 Nov 18
ISSN2192-2659
Abstract

A hydrogel-based dual film coating is electrofabricated for transducing bio-relevant chemical information into electronical output. The outer film has a synthetic biology construct that recognizes an external molecular signal and transduces this input into the expression of an enzyme that converts redox-inactive substrate into a redox-active intermediate, which is detected through an amplification mechanism of the inner redox-capacitor film.

DOI10.1002/adhm.201600908
Alternate JournalAdv Healthc Mater
PubMed ID27863177