|Title||Chitosan-mediated and spatially selective electrodeposition of nanoscale particles.|
|Publication Type||Journal Article|
|Year of Publication||2005|
|Authors||Wu, L-Q, Lee, K, Wang, X, English, DS, Losert, W, Payne, GF|
|Date Published||2005 Apr 12|
|Keywords||Biocompatible Materials, Biosensing Techniques, Chitosan, Electroplating, Fluorescent Dyes, Hydrogen-Ion Concentration, Latex, Nanostructures, Nanotechnology, Particle Size, Spectrometry, Fluorescence|
Nanoscale particles offer a variety of interesting properties, and there is growing interest in their assembly into higher ordered structures. We report that the pH-responsive aminopolysaccharide chitosan can mediate the electrodeposition of model nanoparticles. Chitosan is known to electrodeposit at the cathode surface in response to a high localized pH. To demonstrate that chitosan can mediate nanoparticle deposition, we suspended fluorescently labeled latex nanoparticles (100 nm diameter spheres) in a chitosan solution (1%) and performed electrodeposition (0.05 mA/cm2 for several minutes). Results demonstrate that chitosan is required for nanoparticle electrodeposition; chitosan confers spatial selectivity to electrodeposition; and nanoparticles distribute throughout the electrodeposited chitosan film. Additionally, we observed that the deposited films reversibly swell upon rehydration. This work indicates that chitosan provides a simple means to assemble nanoparticles at addressable locations and provides further evidence that stimuli-responsive biological materials may facilitate fabrication at the microscale.