A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS.

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TitleA fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS.
Publication TypeJournal Article
Year of Publication2005
AuthorsPowers, MA, Koev, ST, Schleunitz, A, Yi, H, Hodzic, V, Bentley, WE, Payne, GF, Rubloff, GW, Ghodssi, R
JournalLab Chip
Volume5
Issue6
Pagination583-6
Date Published2005 Jun
ISSN1473-0197
KeywordsBiomimetics, Biosensing Techniques, Equipment Design, Microfluidics, Microscopy, Fluorescence, Optics and Photonics, Sensitivity and Specificity
Abstract

We report a new approach for microfluidic optical bioanalysis that is based on the electrically driven assembly of bio-components on a transparent sidewall and the optical detection of the assembled components using planar waveguides. This allows localized electrical signals for bio-assembly and optical signals for bio-detection that can easily be applied in MEMS systems. We demonstrate a BioMEMS design incorporating this scheme and its output signal when using fluorescent detection.

DOI10.1039/b503112e
Alternate JournalLab Chip
PubMed ID15915249