|Title||A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS.|
|Publication Type||Journal Article|
|Year of Publication||2005|
|Authors||Powers, MA, Koev, ST, Schleunitz, A, Yi, H, Hodzic, V, Bentley, WE, Payne, GF, Rubloff, GW, Ghodssi, R|
|Date Published||2005 Jun|
|Keywords||Biomimetics, Biosensing Techniques, Equipment Design, Microfluidics, Microscopy, Fluorescence, Optics and Photonics, Sensitivity and Specificity|
We report a new approach for microfluidic optical bioanalysis that is based on the electrically driven assembly of bio-components on a transparent sidewall and the optical detection of the assembled components using planar waveguides. This allows localized electrical signals for bio-assembly and optical signals for bio-detection that can easily be applied in MEMS systems. We demonstrate a BioMEMS design incorporating this scheme and its output signal when using fluorescent detection.
|Alternate Journal||Lab Chip|