Improved metal cluster deposition on a genetically engineered tobacco mosaic virus template.

Printer-friendly versionPrinter-friendly versionPDF versionPDF version
TitleImproved metal cluster deposition on a genetically engineered tobacco mosaic virus template.
Publication TypeJournal Article
Year of Publication2005
AuthorsLee, S-Y, Royston, E, Culver, JN, Harris, MT
JournalNanotechnology
Volume16
Issue7
PaginationS435-41
Date Published2005 Jul
ISSN0957-4484
Abstract

Improved depositions of various metal clusters onto a biomolecular template were achieved using a genetically engineered tobacco mosaic virus (TMV). Wild-type TMV was genetically altered to display multiple solid metal binding sites through the insertion of two cysteine residues within the amino-terminus of the virus coat protein. Gold, silver, and palladium clusters synthesized through in situ chemical reductions could be readily deposited onto the genetically modified template via the exposed cysteine-derived thiol groups. Metal cluster coatings on the cysteine-modified template were more densely deposited and stable than similar coatings on the unmodified wild-type template. Combined, these results confirm that the introduction of cysteine residues onto the outer surface of the TMV coat protein enhances the usefulness of this virus as a biotemplate for the deposition of metal clusters.

DOI10.1088/0957-4484/16/7/019
Alternate JournalNanotechnology
PubMed ID21727464