Coupling electrodeposition with layer-by-layer assembly to address proteins within microfluidic channels.

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TitleCoupling electrodeposition with layer-by-layer assembly to address proteins within microfluidic channels.
Publication TypeJournal Article
Year of Publication2011
AuthorsWang, Y, Liu, Y, Cheng, Y, Kim, E, Rubloff, GW, Bentley, WE, Payne, GF
JournalAdv Mater
Volume23
Issue48
Pagination5817-21
Date Published2011 Dec 22
ISSN1521-4095
KeywordsAlginates, Algorithms, Animals, Aspergillus niger, Brachyura, Chitosan, Electrochemistry, Electroplating, Equipment Design, Glucose Oxidase, Glucuronic Acid, Hexuronic Acids, Lipid Bilayers, Macrocystis, Materials Testing, Microfluidics, Microscopy, Microscopy, Fluorescence, Polymers, Spectrum Analysis, Raman, Surface Properties
Abstract

Two thin-film assembly methods are coupled to address proteins. Electrodeposition confers programmability and generates a template for layer-by-layer (LbL) assembly. LbL enables precise control of film thickness and the incorporation of labile biological components. The capabilities are demonstrated using glucose oxidase (GOx) based electrochemical biosensing within a microfabricated fluidic device.

DOI10.1002/adma.201103726
Alternate JournalAdv. Mater. Weinheim
PubMed ID22102376