Optically clear alginate hydrogels for spatially controlled cell entrapment and culture at microfluidic electrode surfaces.

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TitleOptically clear alginate hydrogels for spatially controlled cell entrapment and culture at microfluidic electrode surfaces.
Publication TypeJournal Article
Year of Publication2013
AuthorsBetz, JF, Cheng, Y, Tsao, C-Y, Zargar, A, Wu, H-C, Luo, X, Payne, GF, Bentley, WE, Rubloff, GW
JournalLab Chip
Volume13
Issue10
Pagination1854-8
Date Published2013 May 21
ISSN1473-0189
Abstract

We describe an innovation in the immobilization, culture, and imaging of cells in calcium alginate within microfluidic devices. This technique allows unprecedented optical access to the entirety of the calcium alginate hydrogel, enabling observation of growth and behavior in a chemical and mechanical environment favored by many kinds of cells.

DOI10.1039/c3lc50079a
Alternate JournalLab Chip
PubMed ID23559159