News Releases

IBBR Investigator to Lead $3.9M NIH-Funded Project to Develop Next-Generation HIV-1 Immunotherapy Agents


Multi-specific anti-HIV antibodies that neutralize almost all circulating HIV-1 viruses will be optimized to target persistent infection

(Rockville, MD, November 20, 2018) IBBR researchers recently received $3.9 million from the National Institutes of Health (NIH) to develop a multi-specific, single agent antibody therapeutic against HIV-1 to block virus infection and to clear the reservoir of HIV-infected cells from the body. 

IBBR welcomes middle school students for Frontiers in Science & Medicine Day


November 16, 2018 -- Thirty-seven seventh graders from Briggs Chaney and Banneker Middle Schools of Montgomery County visited IBBR, on Friday, November 9, for an especially eye-opening and mind-expanding school day.  The Frontiers in Science and Medicine Day program, a collaborative effort among organizations within the Shady Grove Life Sciences Center, is celebrating its tenth year with nearly 600 students participating program-wide.  IBBR has hosted groups of students for nine years of the Frontiers program.

NIST Director and Standards Alumni Association honor former Associate Director of CARB


October 29, 2018 -- Dr. Gary L. Gilliland was honored on Friday morning, October 26th, with a portrait in the National Institute of Science and Technology (NIST) Portrait Gallery of Distinguished Scientists, Engineers and Administrators.  Dr. Gilliland served as the Associate Director of UMBI CARB, a partnership among the University of Maryland College Park (UMCP), Montgomery County, and NIST, from 1991-1996 and from 2002-2003.  CARB later evolved into the University’s Institute for Bioscience and Biotechnology (IBBR), a partnership among UMCP, University of Maryland Baltimore, and NIST.... Read More

IBBR research discovery could be crucial to development of cross-species Ebola vaccines and treatments


October 16, 2018 -- The recent cases of Ebola virus infection in the Democratic Republic of the Congo are an alarming reminder of the 2014 outbreak in West Africa.  IBBR Fellow Dr. Gilad Ofek, Assistant Professor, University of Maryland, College Park Department of Cell Biology and Molecular Genetics, recently solved the crystal structure of a cross-protective antibody bound to an important ebolavirus surface protein. Structural insights from this work lay important groundwork for the development of vaccines and therapeutics effective across all five species of the virus.

IBBR Receives $1.2M NIH Award to Develop 3D Modeling Tool That Could Lead to New Immunotherapies


New computational tool supports the engineering and development of cancer immunotherapies by predicting how T cell receptors recognize and bind to their targets

(Rockville, MD, October 3, 2018)  The Institute for Bioscience and Biotechnology Research (IBBR) has been awarded a $1.2M National Institute of Health (NIH) grant to generate a robust modeling and design framework to predict the structures of T cell receptors (TCRs) from sequence, model antigen recognition, and design new TCRs with desired targeting capabilities that can be applied in therapies against... Read More

Harnessing viral enzymes to combat bacterial infections in dairy cows


October 1, 2018 -- When most of us think about viruses and bacteria, we envision germs that make people sick. But, Dr. Daniel Nelson, IBBR Fellow and Associate Professor, Department of Veterinary Medicine at the University of Maryland College Park, studies viruses that may end up making us well -- by killing disease-causing bacteria. 

IBBR Doctoral Candidate, Tsega Solomon, Travels to Dublin to Present Protein Folding Research


August 30, 2018 -- Tsega Solomon, a doctoral candidate in Dr. John Orban’s laboratory at the Institute for Bioscience and Biotechnology Research (IBBR), attended the XXVIII International Conference on Magnetic Resonance in Biological Systems, at the University College Dublin, Ireland, on August 19-24, 2018.  Solomon’s poster, on temperature-dependent protein fold switching, was chosen as one of the best at the event, for which she received a Suraj Manrao Student Science Fund poster award. 

Orban Presents at Gordon Conference in Switzerland


August 23, 2018 -- IBBR Fellow Dr. John Orban spoke at the Intrinsically Disordered Proteins Gordon Research Conference held in Les Diablerets, Switzerland in early July. Dr. Orban presented work from two systems his team is exploring in his talk titled “Disordered Regions in Ensemble and Fold Switching”.

Montgomery County Students Gain Biotechnology Experience at IBBR


August 23, 2018 -- IBBR’s 2018 Summer Intern program culminated on Thursday, August 16, as six Montgomery County high school students presented their research results to their peers, colleagues, family, and friends at a poster session held at the Institute’s Shady Grove campus. Begun in 2003, the IBBR Summer Intern program has provided approximately 160 local high school students with real-world experience in biology, chemistry, and engineering.

IBBR Researcher, Dr. Alexander Andrianov, Receives Funding for Two Collaborations


Collaborations will explore using two novel types of biofunctional synthetic macromolecules of the polyphosphazene (PPZ) family for exciting and very different applications. 

(Rockville, MD, October 17, 2018) Dr. Andrianov and his collaborator Dr. Svetlana Sukhishvili, of Texas A&M University, have demonstrated that layer-by-layer (LbL) assembly of amphiphilic (containing both hydrophilic and hydrophobic components) PPZs can be employed to create nano-structured fluorinated coatings that display superior biocompatibility. In another... Read More