Agenda

8:00AM Check-In

8:55AM-9:00AM Introduction

9:00AM-10:40AM Talk session 1

Doreen Matthies, NIH, Cryo-EM of a 59 kDa lipid flippase sheds light on its translocation mechanism

Frank Heinrich, Carnegie Mellon and NIST/NCNR, Homodimer formation of HIV-1 Nef at the membrane resolved by neutron reflectometry and molecular modeling.
Marzena Pazgier, USUHS, Fc-effector functions to SARS-CoV2, are they important?

10:40AM-10:55AM Coffee break

10:55AM-11:55AM Keynote talk

Edward Egelman, University of Virginia, Insights into evolution from cryo-EM

11:55AM-12:35PM Lunch

12:35PM-2:15PM Talk session 2

Jana Ognjenovic, NCI, Sub-2 Å structures with the CRYO ARM200: From holes to hydrogens

Robert Best, NIH/NIDDK, Integrating molecular simulations with single molecule FRET to characterize disordered protein assemblies

Aaron Smith, UMBC, Structural insights into eukaryotic post-translational arginylation

2:15PM-3:15PM Poster presentations

3:15PM-4:55PM Talk session 3

Edward C. Twomey, JHU, An adaptable platform for time-resolved cryo-EM with single millisecond precision

Patrick Wintrode, UMB SOP, Integrating HDX-MS and simulations to characterize protein structural ensembles

Jacek Lubkowski, NCI/CCR, Some secrets of L-asparaginase, the oldest enzyme-based cancer drug

4:55PM-5:00PM Concluding remarks

5:00PM-6:00PM Reception