Vaccines
Links
Vaccine Design
Advances in computational design algorithms, coupled with experimental data on the structural basis of immune recognition and pathogenesis of viruses, viral sequence and immune repertoire sequencing, are ushering in a new era of vaccine design to combat emerging and variable viruses.
Hepatitis C vaccine design
We have been studying hepatitis C virus (HCV) and design of vaccines to elicit antibodies to target conserved and functionally critical portions of the viral envelope. Through collaborations with leading HCV researchers, including MassBiologics who recently had their HCV1 mAb in phase 2 clinical trials, we are engineering and testing a number of novel vaccine candidates to effectively target this virus.
Other emerging viruses. We are also exploring vaccines against other viral threats.