Insect Transformation Facility Client Publications

ITF

  1. De Obaldia, Maria Elena, Takeshi Morita, Laura C Dedmon, Daniel J Boehmler, Caroline S Jiang, Emely V Zeledon, Justin R Cross, and Leslie B Vosshall. “Differential Mosquito Attraction to Humans Is Associated with Skin-Derived Carboxylic Acid Levels.” Preprint. Neuroscience, January 5, 2022. https://doi.org/10.1101/2022.01.05.475088.
  2. Younger, Meg A., Margaret Herre, Olivia V. Goldman, Tzu-Chiao Lu, Gabriela Caballero-Vidal, Yanyan Qi, Zachary N. Gilbert, et al. “Non-Canonical Odor Coding in the Mosquito,” January 5, 2022. https://doi.org/10.1101/2020.11.07.368720.
  3. Sorrells, Trevor R., Anjali Pandey, Adriana Rosas-Villegas, and Leslie B. Vosshall. “A Persistent Behavioral State Enables Sustained Predation of Humans by Mosquitoes,” December 24, 2021. https://doi.org/10.1101/2021.10.06.463436.
  4. Inbar, Ehud, Abraham G. Eappen, Robert T. Alford, William Reid, , Maryam Hosseini, Sumana Chakravarty, et al. “Knockout of Anopheles Stephensi Immune Gene LRIM1 by CRISPR-Cas9 Reveals Its Unexpected Role in Reproduction and Vector Competence.” PLoS Pathogens 17, no. 11 (November 16, 2021): e1009770. https://doi.org/10.1371/journal.ppat.1009770.
  5. Billingsley, Peter F., Kasim I. George, Abraham G. Eappen, , Robert Alford, Tao Li, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman, and David A. O’Brochta. “Transient Knockdown of Anopheles Stephensi LRIM1 Using RNAi Increases Plasmodium Falciparum Sporozoite Salivary Gland Infections.” Malaria Journal 20, no. 1 (June 26, 2021): 284. https://doi.org/10.1186/s12936-021-03818-8
  6. Oringanje, Chioma, Lillian R. Delacruz, Yunan Han, Shirley Luckhart, and Michael A. Riehle. “Overexpression of Activated AMPK in the Anopheles Stephensi Midgut Impacts Mosquito Metabolism, Reproduction and Plasmodium Resistance.” Genes 12, no. 1 (January 2021): 119. https://doi.org/10.3390/genes12010119
  7. Louradour, Isabelle, Kashinath Ghosh, Ehud Inbar, David L. Sacks, Channa Aluvihare, and Ii. “Sand Fly (Phlebotomus Papatasi) Embryo Microinjection for CRISPR/Cas9 Mutagenesis.” JoVE (Journal of Visualized Experiments), no. 165 (November 17, 2020): e61924. https://doi.org/10.3791/61924
  8. Sharma, Arvind, Michael N. Pham, Jeremiah B. Reyes, Randeep Chana, Won C. Yim, Chan C. Heu, Donghun Kim, Duverney Chaverra-Rodriguez, Jason Rasgon, et al. “Cas9-Mediated Gene-Editing in the Black-Legged Tick, Ixodes Scapularis, by Embryo Injection and ReMOT Control.” SSRN Scholarly Paper. Rochester, NY: Social Science Research Network, October 8, 2020. https://doi.org/10.2139/ssrn.3691041.
  9. Zhao, Zhilei, Jessica L. Zung, Alexis L. Kriete, Azwad Iqbal, Meg A. Younger, Benjamin J. Matthews, Dorit Merhof, Stephan Thiberge, Martin Strauch, and Carolyn S. McBride. “Chemical Signatures of Human Odour Generate a Unique Neural Code in the Brain of Aedes Aegypti Mosquitoes.” BioRxiv, November 2, 2020, 2020.11.01.363861. https://doi.org/10.1101/2020.11.01.363861.
  10. Jové, Veronica, Zhongyan Gong, Felix J. H. Hol, Zhilei Zhao, Trevor R. Sorrells, Thomas S. Carroll, Manu Prakash, Carolyn S. McBride, and Leslie B. Vosshall. “Sensory Discrimination of Blood and Floral Nectar by Aedes Aegypti Mosquitoes.” Neuron 0, no. 0 (October 12, 2020). https://doi.org/10.1016/j.neuron.2020.09.019.
  11. Cheatle Jarvela, Alys M., Catherine S. Trelstad, and Leslie Pick. “Regulatory Gene Function Handoff Allows Essential Gene Loss in Mosquitoes.” Communications Biology 3, no. 1 (September 30, 2020): 1–10. https://doi.org/10.1038/s42003-020-01203-w.
  12. Meuti, Megan E., and . “Preparing and Injecting Embryos of Culex Mosquitoes to Generate Null Mutations Using CRISPR/Cas9.” JoVE (Journal of Visualized Experiments), no. 163 (September 10, 2020): e61651. https://doi.org/10.3791/61651.
  13. Basrur, Nipun S, Maria Elena De Obaldia, Takeshi Morita, Margaret Herre, Ricarda K von Heynitz, Yael N Tsitohay, and Leslie B Vosshall. “Fruitless Mutant Male Mosquitoes Gain Attraction to Human Odor.” Edited by Kristin Scott and Catherine Dulac. ELife 9 (December 7, 2020): e63982. https://doi.org/10.7554/eLife.63982.
  14. Zhao, Zhilei, David Tian, and Carolyn S. McBride. “Development of a Pan-Neuronal Genetic Driver in Aedes Aegypti Mosquitoes.” Cell Reports Methods 1, no. 3 (July 26, 2021): 100042. https://doi.org/10.1016/j.crmeth.2021.100042.
  15. Maguire, Sarah E., Ali Afify, Loyal A. Goff, and Christopher J. Potter. “A Feedback Mechanism Regulates Odorant Receptor Expression in the Malaria Mosquito, Anopheles Gambiae.” BioRxiv, July 24, 2020, 2020.07.23.218586. https://doi.org/10.1101/2020.07.23.218586.
  16. Afify, Ali, Joshua F. Betz, Olena Riabinina, Chloé Lahondère, and Christopher J. Potter. “Commonly Used Insect Repellents Hide Human Odors from Anopheles Mosquitoes.” Current Biology 0, no. 0 (October 17, 2019). https://doi.org/10.1016/j.cub.2019.09.007.
  17. Louradour, Isabelle, Kashinath Ghosh, Ehud Inbar, and David L. Sacks. “CRISPR/Cas9 Mutagenesis in Phlebotomus Papatasi: The Immune Deficiency Pathway Impacts Vector Competence for Leishmania Major.” MBio 10, no. 4 (August 27, 2019): e01941-19. https://doi.org/10.1128/mBio.01941-19.
  18. Matthews, Benjamin J, Meg A Younger, and Leslie B Vosshall. “The Ion Channel Ppk301 Controls Freshwater Egg-Laying in the Mosquito Aedes Aegypti.” Edited by Kristin Scott, Catherine Dulac, and W Daniel Tracey. ELife 8 (May 21, 2019): e43963. https://doi.org/10.7554/eLife.43963.
  19. Raji, Joshua I., Nadia Melo, John S. Castillo, Sheyla Gonzalez, Valeria Saldana, Marcus C. Stensmyr, and Matthew DeGennaro. “Aedes Aegypti Mosquitoes Detect Acidic Volatiles Found in Human Odor Using the IR8a Pathway.” Current Biology 29, no. 8 (April 22, 2019): 1253-1262.e7. https://doi.org/10.1016/j.cub.2019.02.045.
  20. Qi, Yumin, Yang Wu, Randy Saunders, Xiao-Guang Chen, Chunhong Mao, James Kite Biedler, and Zhijian Jake Tu. “Guy1, a Y-Linked Embryonic Signal, Regulates Dosage Compensation in Anopheles Stephensi by Increasing X Gene Expression.” Edited by Detlef Weigel, Yukiko M Yamashita, Flaminia Catteruccia, and Christine M Disteche. ELife 8 (March 19, 2019): e43570. https://doi.org/10.7554/eLife.43570.
  21. Duvall, Laura B., Lavoisier Ramos-Espiritu, Kyrollos E. Barsoum, J. Fraser Glickman, and Leslie B. Vosshall. “Small-Molecule Agonists of Ae. Aegypti Neuropeptide Y Receptor Block Mosquito Biting.” Cell 176, no. 4 (February 7, 2019): 687-701.e5. https://doi.org/10.1016/j.cell.2018.12.004.
  22. O’Brochta, David A., Robert Alford, , Channa Aluvihare, Abraham G. Eappen, Tao Li, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman, and Peter F. Billingsley. “Is Saglin a Mosquito Salivary Gland Receptor for Plasmodium Falciparum?” Malaria Journal 18, no. 1 (January 3, 2019): 2. https://doi.org/10.1186/s12936-018-2634-5.
  23. Mysore, Keshava, Ping Li, and Molly Duman-Scheel. “Identification of Aedes Aegypti Cis-Regulatory Elements That Promote Gene Expression in Olfactory Receptor Neurons of Distantly Related Dipteran Insects.” Parasites & Vectors 11, no. 1 (December 2018): 406. https://doi.org/10.1186/s13071-018-2982-6.
  24. Souvannaseng, Lattha, Lewis Vibul Hun, Heather Baker, John M. Klyver, Bo Wang, Nazzy Pakpour, Jordan M. Bridgewater, et al. “Inhibition of JNK Signaling in the Asian Malaria Vector Anopheles Stephensi Extends Mosquito Longevity and Improves Resistance to Plasmodium Falciparum Infection.” PLOS Pathogens 14, no. 11 (November 29, 2018): e1007418. https://doi.org/10.1371/journal.ppat.1007418.
  25. Reid, William, Kristina Pilitt, Robert Alford, Adriana Cervantes-Medina, Hao Yu, Channa Aluvihare, , and David A. O’Brochta. “An Anopheles Stephensi Promoter-Trap: Augmenting Genome Annotation and Functional Genomics.” G3: Genes, Genomes, Genetics 8, no. 10 (October 1, 2018): 3119–30. https://doi.org/10.1534/g3.118.200347.
  26. Duvall, Laura B., Nipun S. Basrur, Henrik Molina, Conor J. McMeniman, and Leslie B. Vosshall. “A Peptide Signaling System That Rapidly Enforces Paternity in the Aedes Aegypti Mosquito.” Current Biology 27, no. 23 (December 4, 2017): 3734-3742.e5. https://doi.org/10.1016/j.cub.2017.10.074.
  27. Häcker, Irina, , Gerrit Eichner, Kristina L. Pilitt, David A. O’Brochta, Alfred M. Handler, and Marc F. Schetelig. “Cre/Lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes Aegypti.” Scientific Reports 7 (March 7, 2017). https://doi.org/10.1038/srep43883.
  28. Jupatanakul, Natapong, Shuzhen Sim, Yesseinia I. Angleró-Rodríguez, Jayme Souza-Neto, Suchismita Das, Kristin E. Poti, Shannan L. Rossi, Nicholas Bergren, Nikos Vasilakis, and George Dimopoulos. “Engineered Aedes Aegypti JAK/STAT Pathway-Mediated Immunity to Dengue Virus.” PLOS Neglected Tropical Diseases 11, no. 1 (January 12, 2017): e0005187. https://doi.org/10.1371/journal.pntd.0005187.
  29. Riabinina, Olena, Darya Task, Elizabeth Marr, Chun-Chieh Lin, Robert Alford, David A. O’Brochta, and Christopher J. Potter. “Organization of Olfactory Centres in the Malaria Mosquito Anopheles Gambiae.” Nature Communications 7, no. 1 (October 3, 2016): 13010https://doi.org/10.1038/ncomms13010
  30. Totten, D. C., M. Vuong, O. V. Litvinova, U. K. Jinwal, M. Gulia-Nuss, R. A. Harrell II, and H. Beneš. “Targeting Gene Expression to the Female Larval Fat Body of Transgenic Aedes Aegypti Mosquitoes.” Insect Molecular Biology 22, no. 1 (2013): 18–30. https://doi.org/10.1111/imb.12005.
  31. Robert T. Alford, Kristina L. Pilitt, Channa U. Aluvihare, and Robert A. Harrell. “PiggyBac Transposon Remobilization and Enhancer Detection in Anopheles Mosquitoes.” Proceedings of the National Academy of Sciences 108, no. 39 (September 27, 2011): 16339–44. https://doi.org/10.1073/pnas.1110628108