News Stories
New Study Shows Timing of Ebola Booster Shots Key to Stronger, Lasting Protection
Ebola, a rare but life-threatening condition caused by infection with the Ebola virus, can lead to severe outbreaks with high mortality rates and a global health burden. A recent study published in Nature Immunology, entitled “Improved VSV-Ebola-GP booster vaccination approach promotes antibody affinity maturation and durable anti-Ebola immunity in humans,”...
Fischell Institute Awards Funding to Advance Innovative Biomedical Projects, Including Breakthrough Work by E. Kim
The Fischell Institute for Biomedical Devices has announced $150,000 in funding to support three early-stage faculty-led projects aimed at accelerating the development of transformative medical technologies. Among the awardees is Eunkyoung Kim, whose work could significantly improve how clinicians assess complex psychiatric conditions.
IBBR Ph.D. Student Earns Prestigious 2026 Summer Research Fellowship
IBBR proudly congratulates doctoral student Holly Hemesath on receiving the Graduate Student Summer Research Fellowship for 2026, a competitive award that supports Ph.D. students at critical stages of their training. Holly is a member of Dr. Yanxin Liu’s group at the Institute for Bioscience & Biotechnology Research (IBBR) and in...
About IBBR
IBBR is a joint research enterprise of the University of Maryland, College Park, the University of Maryland, Baltimore, and the National Institute of Standards and Technology.
IBBR leverages state-of-art integrative methods for bioanalytical, biophysical and structural characterization of biomolecules: cryo-electron microscopy, nuclear magnetic resonance, x-ray crystallography, small angle neutron and x-ray scattering and mass spectrometry.
IBBR researchers seek to advance therapeutic development, biomanufacturing, and state-of-the-art measurement technologies, to support accelerated delivery of safe and effective medicines to the public.
IBBR is a major initiative and supported in part by the University of Maryland Strategic Partnership: MPowering the State (MPower) , an initiative designed to achieve innovation and impact through collaboration.
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IBBR Commons
Sophisticated state-of-the-art instrumentation and facilities, and in-house expertise located in shared space and dedicated to advance research, support collaboration and foster innovation of methods. Instrumentation and facilities include tools for high-resolution structural biology, bioanalytical and biophysical measurement, protein engineering and cell culture, advanced computation including artificial intelligence and deep learning methods, and general laboratory services. These capabilities and advanced training are available to IBBR scientists and collaborators.
IBBR Postdoc Program
The IBBR Postdoc Program (IPP) focuses on collaborative research involving basic science and technology development that advances therapeutic development, vaccine development, and biomanufacturing. IPP Fellow project teams are designed with a combination of the IPP Fellow career goals and priorities of project mentors who can be from academic, government, and/or industrial laboratories throughout the University of Maryland, NIST and the I-270 corridor.
NMRPipe
IBBR is home to NMRPipe, a popular collection of programs and scripts for manipulating multidimensional Nuclear Magnetic Resonance (NMR) data. The use of NMRPipe is noted in roughly 40% of all NMR structures accepted into the Protein Data Bank.
Upcoming Events
Seminar: Asher Williams, Columbia University
Recent Publications
Metabolite Fraction Libraries for Quantitative NMR Metabolomics.
Nuclear magnetic resonance (NMR) has unique strengths in metabolomics studies, particularly in quantifying mixtures and elucidating the structures of unknown molecules. One-dimensional (1D) proton...
Glycoengineered Recombinant Alpha1-Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma-Derived Protein.
Alpha-1-antitrypsin (A1AT) is a multifunctional, clinically important, high-value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes,...
The role of MLO in powdery mildew susceptibility depends on a combination of functional specialization and subcellular localization.
Obligate biotrophic powdery mildew (PM) fungi strictly require living hosts to survive. To search for host factors or processes essential for PM pathogenesis, we conducted a tailored forward...
ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter-Strategies.
The endosomal sorting complex required for transport (ESCRT) machinery consists of multiprotein complexes conserved across all eukaryotic lineages that function in several fundamental cellular...